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Detoxicating and blood circulation promoting ointment and its prepn

A technology of detoxification, blood circulation and ointment, applied in the field of external medicine, can solve the problem of long-term or short-term high-dose injection or oral administration of dexamethasone, kangningketong, prednisone, cortisone, destroying the body's defense system and suppressing immune response Ability, local resistance reduction and other problems, to achieve the effect of rigorous and scientific formula, no toxic side effects, easy to absorb

Inactive Publication Date: 2006-05-17
YUNNAN YUYAO BIOPHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the drugs currently used for this type of disease are hormone drugs for external use, oral administration and injection, which have large toxic and side effects. Using these drugs is not only ineffective, but also reduces local resistance, aggravates the condition, and even leads to drug-dependent dermatitis ( Hormone-dependent dermatitis), if long-term external use of hormone preparations, it will also become addicted, and there are about 20 kinds of side effects; Corticosteroids such as corticosteroids such as corticosteroids, or the use of so-called secret preparations containing hormones (patients may not know the truth), the consequences are even more unimaginable. Giving large doses of glucocorticoids for a long time will also cause body sugar, protein, fat, etc. A series of material metabolism disorders such as water and electrolytes and thermoregulation disorders will destroy the body's defense system and suppress immune response capabilities, severely inhibit the hypothalamus-pituitary-adrenal axis, and thus cause a series of more serious side effects and complications. Complications can directly threaten the patient's life

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] main medicine formula

[0050] Catechu 1g Houttuynia cordata 150g Eclipta 300g

[0051] Hematoxylin 100g gallnut 150g double-faced needle 150g

[0052] Menthol 3g

[0053] Excipient formula

[0054] Cetyl Alcohol 53g Simethicone 14g Glyceryl Monostearate 24g

[0055] Liquid paraffin 58g Span 80 19g

[0056] Glycerin 115g Ethylparaben 4g

[0057] Add 7g of sodium lauryl sulfate to water until the total amount of paste is 1000g

[0058] Preparation:

[0059] (1) The above seven medicinal materials, except menthol, the other six flavors such as catechu, washed and dried, crushed into coarse powder, impregnated twice with 70% ethanol for 12 hours each time, combined the impregnated liquid, filtered, and the filtrate was reduced Press to recover ethanol and concentrate to a clear paste with a relative density of 1.20 (50°C);

[0060] (2) Dissolving glycerin, ethyl p-hydroxybenzoate, sodium lauryl sulfate and water in the water phase and heating to 80-85°C to melt to ...

Embodiment 2

[0064] main medicine formula

[0065] Catechu 3g Houttuynia cordata 170g Eclipta 250g

[0066] Hematoxylin 150g Galla chinensis 180g Double-faced needle 100g

[0067] Menthol 1g

[0068] Excipient formula

[0069] White Vaseline 120g Stearyl Alcohol 80g Glyceryl Monostearate 20g

[0070] Propylene Glycol 50g Laurocapzone 40g Glycerin 100g

[0071] Ethyl p-hydroxybenzoate 2g Sodium lauryl sulfate 10g Water added to total amount of paste 1000g

[0072] Preparation:

[0073] (1) is identical with (1) in embodiment 1;

[0074] (2) Take white petrolatum, stearyl alcohol, laurocapram and glycerol monostearate in an oil phase pot and heat to 70-80°C to melt to obtain an oil phase;

[0075] (3) Take sodium lauryl sulfate, ethyl p-hydroxybenzoate and water, place the aqueous phase in a pot and heat to 70-80°C to melt to obtain the aqueous phase;

[0076] (4) Add the water phase to the oil phase at the same temperature, and stir until condensed to obtain an ointment base;

[00...

Embodiment 3

[0079] main medicine formula

[0080] Catechu 5g Houttuynia cordata 200g Eclipta 200g

[0081] Hematoxylin 200g Galla chinensis 100g Double-faced needle 200g

[0082] Menthol 4g

[0083] Excipient formula

[0084] Hydroxyethylcellulose 50g Ethanol 150g Glycerin 150g

[0085] Ethylparaben 5g water is added to the total amount of paste 1000g

[0086] Preparation:

[0087] (1) is identical with (1) in embodiment 1;

[0088] (2) Take hydroxyethyl cellulose and add glycerin, stir evenly, add water to make it fully swell.

[0089] (3) Take menthol and dissolve it with ethanol (1:1), add the clear paste extracted in (1) and ethyl paraben, stir well to dissolve or evenly disperse.

[0090] Add (3) to (2), stir well, and add water to 1000g, stir evenly to obtain gel.

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PUM

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Abstract

The detoxicating and blood circulation promoting ointment is prepared with seven kinds of Chinese medicinal materials, including catechu, cordate houttuynia, yerbadetajo herb, brazil wood, gallnut, pricklyash root and menthol in certain weight proportion. The detoxicating and blood circulation promoting ointment is oil-in-water or water-in-oil emulsion preparation or water soluble gel applied directly onto the affected part. It has the functions of killing bacteria, diminishing inflammation, killing parasite, eliminating swelling, dissipating mass, etc. and is used in treating soft tissue injury, superficial burns and scalds, scabies, insect bite, arthritis and other diseases. It has fast and obvious treating effect, no toxic side effect, low cost and convenient use.

Description

technical field [0001] The invention relates to the technical field of external medicines, in particular to Qiwei Jiedu Huoxue Ointment which has antibacterial and anti-inflammatory effects and is suitable for treating soft tissue injuries, superficial burns, scalds, scabies and other skin diseases and a preparation method thereof. Background technique [0002] People living in the natural environment will inevitably suffer from various soft tissue sprains, superficial burns, scalds, skin pimples, itching caused by mosquito bites or other skin diseases, arthritis, frozen shoulder and other skin diseases. Skeletal inflammation, severe cases of these diseases can cause redness and swelling of the skin, swelling of the joints, and even deformation. Most of the drugs currently used for this type of disease are hormone drugs for external use, oral administration and injection, which have large toxic and side effects. Using these drugs is not only ineffective, but also reduces loc...

Claims

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Application Information

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IPC IPC(8): A61K36/87A61K35/64A61P17/02
Inventor 高家雄
Owner YUNNAN YUYAO BIOPHARM CO LTD
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