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Enteral composition for the prevention and/or treatment of sepsis

A composition, sepsis technology, applied in the field of enteral composition, can solve problems such as undiscovered medium-chain triglycerides

Inactive Publication Date: 2006-07-12
NV NUTRICIA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, medium chain triglycerides have not been found to be effective in the neutralization of LPS or the formation of chylomicrons

Method used

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  • Enteral composition for the prevention and/or treatment of sepsis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0094] Nutrient for tube feeding, which contains per 100ml:

[0095] Energy 125 kcal

[0096] Protein 1 7.5g

[0097] Sugar 1 14.5g

[0098] Lipids 4.2g includes:

[0099] Phospholipids 2.1g

[0100] Triglycerides 1 0.66g

[0101] Triglycerides 2 1.44g

Embodiment 2

[0104] Tube feeding nutrition which contains per 100ml:

[0105] Energy 100 kcal

[0106] Protein 2 4.0g

[0107] Sugar 2 12.3g

[0108] Lipids 3.9g. Contains:

[0109] Phospholipids 2.0g

[0110] Triglycerides 1 0.63g

[0111] Triglycerides 2 1.27g

[0112] Fiber 1g

Embodiment 3

[0114] Liquid nutrition as a supplement (suck-feed), which contains per 100ml:

[0115] Energy 100 kcal

[0116] Protein 2 4g

[0117] Sugar 3 8.8g

[0118] Lipids 5.4g includes:

[0119] Phospholipids 3.6g

[0120] Triglycerides 1 1.19g

[0121] Triglycerides 2 0.61g

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Abstract

Enteral compositions and use thereof, which compositions contain proteins and lipids, for the prevention and / or treatment of sepsis; the lipid fraction being particularly rich in phospholipids.

Description

technical field [0001] The present invention relates to an enteral composition comprising protein and lipid for preventing and / or treating endotoxemia, sepsis or bacteremia and its application. Background technique [0002] Sepsis is a disease that occurs when relatively large numbers of microorganisms or their fragments enter the body. It is characterized as a systemic disease associated with the presence and persistence of pathogenic microorganisms or their toxins in the blood. If fragments of the bacteria, known as bacterial endotoxins, appear in the blood, this condition is also known as endotoxemia or endotoxic shock. When microorganisms that enter the bloodstream are viable, the condition is also known as bacteremia. Endotoxin or lipopolysaccharide (LPS) is a component of the outer cell membrane of Gram-negative bacteria. Lipoteichoic acid (LTA) and peptidoglycan (PG) are components of the outer membrane of Gram-positive bacteria, which can also cause sepsis. The i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/30A23L1/29A23K1/16A61K31/685A23J7/00A23L33/00A61K35/54A61K35/57A61K36/185A61K36/28A61K36/286A61K36/31A61K36/35A61K36/48A61K36/63A61K36/889A61K36/899A61K45/06
CPCA23J7/00A61K45/06A61K36/48A61K36/35A61K35/57A61K36/31A61K36/185A61K35/60A23V2002/00A61K36/63A61K36/899A61K35/54A23L1/296A23L1/3006A61K36/28A61K36/286A61K36/889A61K31/685A23L33/40A23L33/115A61P31/04A61P39/02A61P43/00A61P7/00A23V2250/54246A23V2250/61A23V2250/616A23V2250/5114A23V2250/1846A23V2250/1848A23V2250/194A23V2250/628
Inventor 杰尔斯科·斯皮尔曼斯阿德里安努斯·约翰努斯·马里亚·弗里塞马安妮塔·科琳娜·欧根妮·弗罗格登希尔威廉·安德里斯·布于尔曼约翰内斯·威廉默斯·马里亚·格雷韦赞德里·霍夫曼英格·基维特罗伯特·约翰·约瑟夫·哈格曼
Owner NV NUTRICIA
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