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Red salvia root and ligustrazine transfusion liquid and its preparation process

A technology of ligustrazine and ligustrazine hydrochloride, which is applied in the field of medicine and can solve problems such as the undeveloped infusion of salvia ligustrazine and ligustrazine

Inactive Publication Date: 2006-10-11
肖广常 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In clinical application, salvia miltiorrhiza and ligustrazine hydrochloride have a good synergistic effect, and its medication method adopts intravenous drip, and there is no report on the development of salvia miltiorrhiza and ligustrazine hydrochloride infusion

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1: Salvia miltiorrhiza and Ligustrazine infusion, the components are as follows

[0024] Danshen 200g

[0025] Ligustrazine Hydrochloride 20g

[0026] Glucose 5000g

[0027] Sodium chloride 450g

[0028] Glycerin 10000ml

[0029] Edetate Disodium 5g

[0030] Add water for injection to 100L

[0031] Makes 1000 applied units.

[0032] The preparation method is as follows:

[0033] Take 200g of Salvia miltiorrhiza, extract it with water, treat it with lime sulfur, and precipitate it twice with alcohol (the first time to make the alcohol content reach 60%, and the second time make the alcohol content reach 70%), recover ethanol, and make each 1ml A clear liquid containing 4g of medicinal materials, adjust the pH value, and use it as a spare medicinal liquid. Take Ligustrazine Hydrochloride 20g, Glycerin 20L, Edetate Disodium 5g, Sodium Chloride 450g, Glucose 5000g and the above medicinal solution, mix them evenly, add water for injection to dissolve. Adjust...

Embodiment 2

[0034] Embodiment 2: Salvia miltiorrhiza and Ligustrazine infusion, the components are as follows

[0035] Danshen 50g

[0036] Ligustrazine Hydrochloride 5g

[0037] Sodium chloride 4500g

[0038] Polyethylene glycol 400 25000ml

[0039] Add water for injection to 500L

[0040] Makes 1000 applied units.

[0041] The preparation method is the same as in Example 1.

Embodiment 3

[0042] Embodiment 3: Salvia miltiorrhiza and Ligustrazine infusion, the components are as follows

[0043] Danshen 200g

[0044] Ligustrazine 20g

[0045] Glucose 5000g

[0046] Add water for injection to 50L

[0047] Makes 1000 applied units.

[0048] The preparation method is the same as in Example 1.

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PUM

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Abstract

The invention relates to a transfusion for treating obliteration cerebrovascular diseases and its preparing process, wherein the transfusion is prepared from radix salvia miltiorrhiza 50-400g, hydrochloric ligustrazine 5-40g, osmoregulation agent 450-50000g, stabilizing agent 0-150000g, water for injection 50-500L. The medicament can be used for intra-vascular instillation.

Description

(1) Technical field [0001] The invention relates to an infusion of salvia miltiorrhiza and ligustrazine and a preparation method thereof, belonging to the technical field of medicine. (2) Background technology [0002] According to relevant survey reports, there are more than 3 million people who die from cardiovascular and cerebrovascular diseases in my country every year, accounting for 50% of the total number of deaths in my country every year. What is even more worrying is that 80% of adults over the age of 30 in my country suffer from cardiovascular and cerebrovascular diseases such as hyperlipidemia, high blood pressure, coronary heart disease, and cerebral apoplexy to a greater or lesser extent. Therefore, the research and development of drugs for the treatment of cardiovascular and cerebrovascular diseases with definite curative effect has become a current need. [0003] Salvia miltiorrhiza belongs to the Lamiaceae plant and mainly grows in China's Hebei, Shaanxi, J...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/53A61K9/08A61K31/496A61P3/06A61P9/10A61P9/12
Inventor 肖广常张颖
Owner 肖广常
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