Method for preparing traditional Chinese herbs or natural product extract to make component stable
A technology of natural products and extracts, applied in the field of blending, can solve the problems of sample representativeness, unstable uniformity, low cost of materials, and large dosage.
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Embodiment 1
[0136] Embodiment 1: Using the method of the present invention to blend the salvia miltiorrhiza extract and ensure that the content of the index components of the blended product is stable
[0137] Salvia miltiorrhiza is the main raw material of Danshen injection water injection and powder injection, and also an important raw material of other injections such as Xiangdan injection. In this example, salvianolic acid B, danshensu, and protocatechualdehyde are listed as index components that need to be controlled in content. A total of 58 batches of wild and cultivated Danshen medicinal materials were collected and purchased nationwide, including 14 wild batches and 44 planted batches. The medicinal materials were identified by the Institute of Traditional Chinese Medicine and Natural Products.
[0138] The goal of setting this embodiment is to investigate whether the extract blending method of the present invention can ensure that the index component content Cm of the extract bl...
Embodiment 2
[0282] Embodiment 2: Adopt the method of the present invention to blend the salvia miltiorrhiza extract and ensure that the index component content of the blended product is stable
[0283] In order to fully reflect the application effect of the present invention, the purpose of setting this example is to illustrate the application mode in which the present invention can impose mandatory requirements on the amount of extracts and allow different upper and lower limit deviations of component content in the constraint conditions.
[0284] The symbols in this embodiment have the same meanings as those in Embodiment 1. Step 1 of this embodiment is the same as that of Embodiment 1, that is, Cs=(3.63 0.49 0.074) T . Step 2 of this embodiment sets c l =(0.08 0.10 0.16) T , c u =(0.20 0.10 0.08) T , at this time the allowable ranges of the contents of the three components are different; the similarity constraint is not considered. Step 3 of this embodiment is the same as that of...
Embodiment 3
[0288] Embodiment 3: Using the method of the present invention to blend the salvia miltiorrhiza extract and ensure that the content of the index components of the blended product is stable
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