Medicine for treating diabetes and hephrosis and its preparing method

A technology for diabetic nephropathy and drugs, which is applied in drug combinations, pharmaceutical formulations, urinary system diseases, etc., can solve problems such as the content of components and preparation methods of "Shenkang Pill" that are not involved

Inactive Publication Date: 2007-01-24
SOUTHERN MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present inventor published an article entitled "Shenkang Pills Effects NO, TGF-β Secretion by Glomerular Mesangial Cells of Rats with Early Diabetic Nephropathy" on "Journal of First Military Medical University" 2006 4th issue. 1 Influence of "The Influence", the article discloses that the "Shenkang Pill" is composed of eight raw materials such as astragalus, leech, corn silk, Gorgon fruit, golden cherry, motherwort, cicada slough, and hawthorn. The mechanism of action of "Shenkang Pills" was explored, and the prescription of "Shenkang Pills" was explained, but the content of components and preparation methods of "Shenkang Pills" were not involved

Method used

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  • Medicine for treating diabetes and hephrosis and its preparing method
  • Medicine for treating diabetes and hephrosis and its preparing method

Examples

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example 1

[0135] Example 1: (pills)

[0136] 1. Prescription: take astragalus 100g, leech 25g, corn silk 100g, gorgon fruit 100g, golden cherry fruit 100g, motherwort 50g, cicada slough 25g, hawthorn 100g.

[0137] 2. Preparation method: the above 8 medicinal materials are purified, and the corn silk and motherwort are extracted twice. For the first time, add 8 times the amount of water to heat and extract for 2 hours, filter, and for the second time, add 6 times the amount of the residue Water was extracted for another 2 hours, filtered, the two extracts were combined, concentrated to 1:1, centrifuged, the supernatant was taken, concentrated to a specific gravity of 1.2, spray-dried to obtain extract powder. The remaining six herbs are dried at 70°C, crushed into fine powder, and mixed with the above-mentioned extract powder. Flood the pills with cold water, dry, select the pills, wrap black iron oxide coat, polish with Sichuan wax, pack separately, and make 6g×1 pills.

[0138] 3. P...

example 2

[0140] Example 2: (pills)

[0141] 1. Prescription: Take 200g astragalus, 40g leech, 125g corn silk, 125g Gorgon fruit, 125g golden cherry, 70g motherwort, 40g cicada slough, and 125g hawthorn.

[0142] 2. Preparation method: the above 8 medicinal materials are purified, and the corn silk and motherwort are extracted twice. For the first time, add 8 times the amount of water to heat and extract for 2 hours, filter, and for the second time, add 6 times the amount of the residue Water was extracted for another 2 hours, filtered, the two extracts were combined, concentrated to 1:1, centrifuged, the supernatant was taken, concentrated to a specific gravity of 1.2, spray-dried to obtain extract powder. The remaining six herbs are dried at 70°C, crushed into fine powder, and mixed with the above-mentioned extract powder. Flood the pills with cold water, dry, select the pills, wrap black iron oxide coat, polish with Sichuan wax, pack separately, and make 6g×1 pills.

[0143] 3. Ide...

example 3

[0145] Example 3: (pills)

[0146] 1. Prescription: take astragalus 300g, leech 50g, corn silk 150g, gorgon fruit 150g, golden cherry fruit 150g, motherwort 75g, cicada slough 50g, hawthorn 150g.

[0147] 2. Preparation method: the above 8 medicinal materials are purified, and the corn silk and motherwort are extracted twice. For the first time, add 8 times the amount of water to heat and extract for 2 hours, filter, and for the second time, add 6 times the amount of the residue Water was extracted for another 2 hours, filtered, the two extracts were combined, concentrated to 1:1, centrifuged, the supernatant was taken, concentrated to a specific gravity of 1.2, spray-dried to obtain extract powder. The remaining six herbs are dried at 70°C, crushed into fine powder, and mixed with the above-mentioned extract powder. Flood the pills with cold water, dry, select the pills, wrap black iron oxide coat, polish with Sichuan wax, pack separately, and make 6g×1 pills.

[0148] 3. P...

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Abstract

The medicine for treating diabetic nephropathy is prepared with astragalus root, leech, corn stigma, gordon euryale seed, Cherokee roe hip and other three kinds of Chinese medicinal materials, and through separate water extraction, stoving, crushing, mixing and other steps to form bolus, tablet, granule or capsule. The medicine has high curative effect on diabetic nephropathy.

Description

Technical field: [0001] The invention relates to a medicine for treating diabetic nephropathy and a preparation method thereof, in particular to a Chinese patent medicine made from Chinese herbal medicines. Background technique: [0002] Diabetic nephropathy (Diabetic nephropathy, DN) is one of the most common and serious systemic microvascular complications in patients with diabetes mellitus (DM). With the improvement of people's living standards, the incidence rate has been increasing year by year, and it is difficult to reverse the disease after entering the clinical DN stage. It is reported abroad that DN can occur in about 40% of type 1 DM and 5-20% of type 2 DM patients. According to domestic reports on 642 cases of diabetic nephropathy survey, the total incidence of DN was 47.66%, of which 34% were early stage and 13.5% were clinical DN. In the United States, 30% of dialysis patients are DN patients, and 27% to 31% of DM patients (diagnosed under the age of 31) suff...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/20A61K9/48A61P3/10A61P13/12A61K35/62A61K35/56A61K35/64
Inventor 魏连波魏凤环佟丽肖炜龙海波
Owner SOUTHERN MEDICAL UNIVERSITY
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