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Traditional medicine composition, its preparation and usage

A composition and technology of traditional Chinese medicine, applied in the field of medicine, can solve problems such as fever and leukopenia

Inactive Publication Date: 2007-02-28
郑涛 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are two main categories of antiviral western medicines that are recognized by the domestic and foreign medical circles to be effective in treating chronic hepatitis B: alpha interferon and nucleoside analogues, but there may be toxic side effects such as fever and leukopenia

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] [embodiment 1] tablet preparation of medicine of the present invention

[0032] Take 1000g of Smilax smilax powder, dissolve it in methanol 2-5 times the weight of the powder, concentrate the methanol extract under reduced pressure, add 7-10 times the amount of water to the residue to dissolve, add 1-3 times the amount of ether to the obtained aqueous solution, and obtain a solution layer and an ether solution layer, take the aqueous solution layer, add 2-5 times of n-butanol for extraction, and evaporate the obtained n-butanol solution to dryness under reduced pressure to obtain white amorphous powder or colorless crystals, which are total saponins of Smilax smilax.

[0033] Take 1000g of flea powder, dissolve it with 2-5 times the weight of the powder in methanol, concentrate the methanol extract under reduced pressure, add 7-10 times the amount of water to the residue to dissolve, add 1-3 times the amount of ether to the resulting aqueous solution, and obtain a soluti...

Embodiment 2

[0036] [embodiment 2] the capsule preparation of medicine of the present invention

[0037] Take 1000g of Smilax smilax powder, dissolve it in methanol 2-5 times the weight of the powder, concentrate the methanol extract under reduced pressure, add 7-10 times the amount of water to the residue to dissolve, add 1-3 times the amount of ether to the obtained aqueous solution, and obtain a solution layer and an ether solution layer, take the aqueous solution layer, add 2-5 times of n-butanol for extraction, and evaporate the obtained n-butanol solution to dryness under reduced pressure to obtain white amorphous powder or colorless crystals, which are total saponins of Smilax smilax.

[0038] Take 1000g of flea powder, dissolve it with 2-5 times the weight of the powder in methanol, concentrate the methanol extract under reduced pressure, add 7-10 times the amount of water to the residue to dissolve, add 1-3 times the amount of ether to the resulting aqueous solution, and obtain a s...

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PUM

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Abstract

The invention discloses a Chinese pharmaceutical composition, its preparing process and use, wherein the composition comprises smixlax glabra total saponin 1-20 parts, Pariphyllin 1-30 parts which are extracted through n-butanol extraction method. The composition can be used for treating chronic hepatitis B and related diseases, and can be prepared into any conventional oral dose types.

Description

【Technical field】 [0001] The invention relates to a traditional Chinese medicine composition, a preparation method and application thereof, and belongs to the field of medicine. 【Background technique】 [0002] Chronic hepatitis B is a chronic, infectious disease caused by the hepatitis B virus (HBV), which seriously endangers health and affects the quality of life. HBV infection is globally distributed, probably over half of the world's population has been infected, with 50 million new infections and 1 million deaths per year. About 5% of the world's population is chronic HBsAg carriers. According to statistics, the current HBV infection rate in my country is as follows: anti-HBc and / or anti-HBs positive people are about 60%; non-infected people account for 26%; chronic hepatitis B is up to 2%; HBsAg positive chronic asymptomatic HBsAg carriers 10%; HBsAg-negative chronic asymptomatic HBV carriers 2%. It can be seen that the epidemic situation of hepatitis B in my country ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P31/20A61P1/16
Inventor 郑涛刘红杰
Owner 郑涛