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Lipase activity inhibitor containing high-molecular weight polyphenol fraction, tea extract and process for producing the same

A technology of activity inhibitor and tea extract, which is applied in the field of lipase activity inhibitor, tea extract and its manufacture containing high molecular polyphenol components, can solve unknown problems and achieve high safety, The effect of inhibiting lipase activity

Active Publication Date: 2007-02-28
SUNTORY HLDG LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, an effective method for selectively separating polymerized catechins and non-polymerized catechins using an adsorbent such as activated carbon or an adsorption resin is not yet known.

Method used

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  • Lipase activity inhibitor containing high-molecular weight polyphenol fraction, tea extract and process for producing the same
  • Lipase activity inhibitor containing high-molecular weight polyphenol fraction, tea extract and process for producing the same
  • Lipase activity inhibitor containing high-molecular weight polyphenol fraction, tea extract and process for producing the same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] tea extraction

[0069] (1) The extraction efficiency of solid components in oolong tea was compared when 1.67 g of sodium bicarbonate was dissolved in 1 L of warm water at 90°C (pH value was 8.22) and when no sodium bicarbonate was added (pH value was 6.79). 100 g of oolong tea leaves were added to each of 1 L of warm water, and the mixture was extracted by stirring slowly for 20 minutes while maintaining the temperature at 90°C.

[0070] When measuring the Brix concentration and pH value of the extract, the Brix was 3.76 and the pH value was 5.06 without sodium bicarbonate, and the Brix was 4.27 and the pH value was 6.15 when sodium bicarbonate was added. As a result of using sodium bicarbonate, it can be clearly seen from the appearance that a concentrated extract is obtained, and this increase in the extraction of solid components can also be confirmed from the Brix value.

[0071] (2) Dissolve 1.67 g of sodium bicarbonate in 1 L of warm water at 90° C., and add 10...

Embodiment 2

[0080] separate

[0081] After degassing, 50 ml of commercially available granular activated carbon (for example, GW-H32 / 60 manufactured by Kuraray Co., Ltd.) was packed into a chromatography column. Here, the oolong tea extract obtained in Example 1 was used to flow at a flow rate of SV=3, and the components were separated. At this time, the temperatures of the extract and the column were set at 20, 40, 50, and 60° C., and the analytical values ​​of the separated liquids separated into about 5 CV are shown in Table 2.

[0082] polymerized catechin

[0083] In this way, the higher the temperature is, the more selectively the non-polymerized catechin can be separated and removed during separation. Figure 1 shows an example of changes in components during separation at 60°C.

Embodiment 3

[0085] Trial manufacturing

[0086] With 0.15% sodium bicarbonate solution (95 DEG C), 600kg of oolong tea leaves are extracted by chromatographic column method to obtain about 6000Kg of extract. The liquid temperature was kept at 60 to 65° C., and non-polymerized catechin and caffeine were selectively removed by passing through 400 kg of granular activated carbon (GW-H32 / 60 manufactured by Kuraray Co., Ltd.). The passage liquid was concentrated under reduced pressure to prepare about 900 kg of a tea extract having a Brix of 10 or more.

[0087] The polymerized catechin (OTPP) in the obtained tea extract was 14648 ppm, and the adsorbed catechin (EGCG+GCG+ECG+CG) was 366 ppm accordingly.

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PUM

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Abstract

There are provided foods and beverages that will suppress the absorption of dietary lipids, thereby suppressing the rise of triglyceride in blood. High-molecular weight polyphenol fractions recovered from oolong tea are added to foods or beverages as an active ingredient for inhibiting lipase activity. The foods and beverages of the present invention are safe and their inherent flavor has not been impaired; hence, they may be taken in routinely so that the lipase inhibitory action of the high-molecular weight polyphenol fractions will suppress the rise of triglyceride in blood and prevent obesity.

Description

technical field [0001] The present invention focuses on the polymer polyphenols (polymerized catechins) contained in teas such as oolong teas, which have various effects and are different from other tannins and non-polymerized catechins in that they have less astringency and bitterness. A method for selectively isolating polymerized catechins in tea and the like, a composition such as tea extracts obtained by concentrating the polymerized catechins obtained by the method, a lipase activity inhibitor containing the components obtained by the method, and The food and drink that does not damage the flavor when the composition is added, has high palatability, and is aimed at improving health. Background technique [0002] In recent years, with the Westernization of the Japanese lifestyle, the intake of high-fat foods has also been increasing. According to the report of the National Nutrition Survey in 2011, although the intake of energy is decreasing year by year, it can exceed...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/765A23F3/18A23L1/30A61K36/82A61P3/04A61P3/06A61P43/00C12N9/99A23L33/20A61K36/00
CPCC07D311/62A61K31/765A23L1/307A23F3/18C07D403/00A61K36/82A23L33/20A61P3/04A61P3/06A61P43/00
Inventor 松原仁志石仓义之佐佐木裕昭阿部圭一浅见纯生中井正晃楠本晶
Owner SUNTORY HLDG LTD
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