A medicinal composition for treating gout

A composition and drug technology, applied in the directions of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of high price of benzbromarone, limited output, gastrointestinal reactions and the like

Inactive Publication Date: 2007-04-11
荣凯
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Probenecid, also known as carboxybenzenesulfonamide, only controls the blood uric acid content during the intermittent period of gout, and has no therapeutic effect on acute gout; colchicine is an alkaloid extracted from Liliaceae plants, which only relieves pain during the acute attack of gout. But it is not effective for chronic gout, because it is extracted from plants, so the output is limited; allopurinol, also known as allopurinol, is the only one that can effectively reduce the production of uric acid, lower the level of uric acid in blood and urine to treat primary gout However, its toxic and side effects are mainly bone marrow suppression, and the pancytopenia caused by it is related to the dosage of the drug. In addition, the blood concentration of allopurinol also depends on whether the kidney function is sound; benzbromarone, also known as benzbromocoumarone Toxic acid, gout lixian, etc. are powerful diuretic drugs, which have been widely used in Europe for many years. They have mild toxic effects and do not affect liver and kidney functions. Rash and fever rarely occur, but gastrointestinal reactions and renal colic may occur. and provoke acute arthritis attacks
In recent years, the market sales are good and it is popular in clinical practice, but the price of benzbromarone is relatively expensive, especially imported drugs and packaged drugs

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0019] 1 tablet formula and preparation method (made into 1000 tablets):

[0020] Analgin 100g

[0021] Vitamin B 6 40 grams

[0022] Ketoprofen 100g

[0023] Wild Papaya Dried Extract 320g

[0024] Prednisone Acetate 20g

[0025] Naproxen 40g

[0026] Sodium bicarbonate 200g

[0027] Calcium Carbonate Appropriate amount

[0028] Appropriate amount of talcum powder

[0029] 10% starch slurry appropriate amount

[0030] Moderate amount of low-substituted hydroxypropyl cellulose

[0031] Grind the above-mentioned raw materials into fine powder, pass through a 100-mesh sieve; mix the auxiliary materials (calcium carbonate, low-substituted hydroxypropyl cellulose) in an equal amount incremental method, and pass through a 80-mesh sieve 3-4 times to fully mix; Add 10% starch slurry to the mixture to make soft materials, pass through 24 mesh to make wet granules, and dry them in a ventilated oven at 55-60°C; add talcum powder after the dry granules are sized th...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
diameteraaaaaaaaaa
Login to View More

Abstract

This is a medical composition for treating gout composed with analgin, ketoprofen, dry extract of stauntonvine, acetate prednisone, naproxen, vitamin B 6 and sodium bicarbonate. The medical composition is reasonable designed with obvious curative effect and fast effectiveness in treat gout. It is easy to take in with no rebound after stopping the medicine. There are complementary actions between the said medical ingredients with no harmfulness. The composition is a common medicine that can be used for long time but with low costs. It is safe, and its quality can be controlled.

Description

technical field [0001] The invention relates to a medicine composition for treating gout, in particular to a Chinese and Western medicine composition for treating gout. Background technique [0002] Gout is a very stubborn disease, a frequently-occurring disease in recent years, which is closely related to the improvement of people's living standards. Gout, which can occur at any age, is a syndrome caused by metabolic disorders of purine substances in the body. Clinically, it has the characteristics of recurrent acute arthritis, gout stones, increased blood uric acid concentration, joint deformities and kidney lesions. [0003] Over the years, there have been few anti-gout drugs on the Chinese pharmaceutical market, mainly Western medicines for gout, and traditional Chinese medicines for gout are basically immature and have poor efficacy. For more than a decade, no new and better anti-gout drugs have been developed in the market, and four drugs, probenecid, colchicine, all...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & AuthorityApplications(China)
IPC IPC(8): A61K36/732A61P19/06A61K31/573A61K31/4415A61K31/4152A61K31/192A61K33/00
Inventor荣凯
Owner荣凯