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A Chinese traditional medicinal composition for treatment of migraine and its preparation method

A composition and technology for migraine, applied in the directions of drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of no consensus, complex pathogenesis of migraine, and inability to provide effective guidance.

Active Publication Date: 2007-04-11
四川梓橦宫药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This is related to the complex pathogenesis of migraine, there is no consensus at present, and there is a lack of reliable auxiliary diagnostic methods
[0004] At present, there is still a lack of in-depth research on the etiology of migraine, and the few theoretical discussions are only circular arguments around the old frame, lacking clear conclusions and innovative insights. Both restrict drug research, resulting in the lack of specificity and specificity of migraine pharmacodynamic research indicators, which cannot provide strong guidance for clinical practice

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] [Prescription] Chuanxiong 150g Gastrodia elata 100g Chrysanthemum 125g

[0046] Vitex 83g Ligusticum 83g Paeoniae Alba 100g

[0047] Salvia 125g Eclipta 300g Ligustrum 83g

[0048] Achyranthes knuckle 83g

[0049] [Preparation method] The above ten flavors, Gastrodia elata are crushed into fine powder; Salvia miltiorrhiza is extracted with 85% ethanol under reflux for 1.5 hours, and then added with 50% ethanol for reflux extraction twice, each time for 1 hour, the filtrates are combined, ethanol is recovered under reduced pressure, and dried to dryness Extract; extract volatile oil from Rhizoma Chuanxiong, Vitex, Ligusticum and Chrysanthemum, filter the distilled aqueous solution, concentrate the filtrate to a relative density of 1.20-1.25 (60°C), and set aside; medicine dregs mixed with Radix Paeoniae Alba, Eclipta, Add water to decoct Zhenzi and Achyranthes bidentata for three times, extract for 2, 1, and 1 hour respectively, filter, combine ...

Embodiment 2

[0051] [Prescription] Chuanxiong 300g Gastrodia elata 200g Chrysanthemum 250g

[0052] Vitex 166g Ligusticum 166g Paeoniae Alba 200g

[0053] Salvia 250g Eclipta 300g Ligustrum 166g

[0054] Achyranthes knuckle 166g

[0055] [Preparation method] The above ten flavors, Gastrodia elata are crushed into fine powder; Salvia miltiorrhiza is extracted with 85% ethanol under reflux for 1.5 hours, and then added with 50% ethanol for reflux extraction twice, each time for 1 hour, the filtrates are combined, ethanol is recovered under reduced pressure, and dried to dryness Extract; extract volatile oil from Rhizoma Chuanxiong, Vitex, Ligusticum and Chrysanthemum, filter the distilled aqueous solution, concentrate the filtrate to a relative density of 1.20-1.25 (60°C), and set aside; medicine dregs mixed with Radix Paeoniae Alba, Eclipta, Add water to decoct Zhenzi and Achyranthes bidentata for three times, extract for 2, 1, and 1 hour respectively, filter, comb...

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Abstract

This invention relates to a Chinese traditional medicinal composition for treatment of migraine belonging to the field of the Chinese traditional medicine. The composition is prepared by using chuanxiong ligusticum rhizome, Tall gastrodia tuber, flos chrgsanthemi, rhizoma chuanxiong etc in accordance with a certain ratio and a special processing technology. It has obvious curative effect in treating migraine. This invention also reveals its preparing method.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating migraine with liver wind stasis syndrome and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Migraine is a common disease and multiple neurological diseases. It is a throbbing headache disease with intermittent and recurrent attacks, mainly on one side, often accompanied by visual, sensory, motor, emotional and gastrointestinal autonomic disorders. Symptoms of dysfunction. [0003] According to a report from the United States, about 28 million American adults are affected by migraine, mainly adults aged 25 to 55 who are at their peak working capacity. About 6% of men and 18% of women experience more than one migraine attack every year, and 85% of women and 82% of men lose their ability to work during migraine attacks, and 1 / 3 of the patients need to rest in bed. The annual economic loss caused by this c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61K9/16A61K9/20A61K9/48A61P25/06A61P29/00
Inventor 周小明
Owner 四川梓橦宫药业股份有限公司