Pesticide preparation containing saturated guinary heterocyclic compound and its use
A five-membered heterocycle, pesticide preparation technology, applied in the directions of biocides, animal repellents, plant growth regulators, etc., can solve the problems of low biodegradability, secondary pollution, low efficacy, etc. Simple, easy to accept, the effect of improving physiological function
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Embodiment 1
[0039] The synthesis of embodiment 1, (1α~1f)
[0040] Install a 250mL two-neck round bottom flask on an electromagnetic stirrer, and equip it with a water separator and a thermometer. Add 1mol of furfural, then add 1~1.2mol of diol or mercaptan or its derivatives and 100~150ml of solvent, and 1~10g of solid catalyst, mix and pour into the reactor, then install the upper water separator, use conventional Methods Reflux and divide water for 4-12 hours, remove the solvent, and distill under reduced pressure to obtain the following (1a-1f) saturated five-membered heterocyclic compounds.
[0041]
[0042] 1a: X 1 =X 2 =O,R 1 =CH 3 , R 2 =H
[0043] 1b:X 1 =X 2 =O,R 1 =CH 2 Cl, R 2 =H
[0044] 1c:X 1 = S, X 2 =O, R 1 =R 2 =H
[0045] 1d: X 1 = S, X 2 =O, R 1 =CH 3 , R 2 =CH 3
[0046] 1e: X 1 =X 2 = S, R 1 =R 2 =H
[0047] 1f: X 1 =X 2 =O,R 1 =CH2 OH,R 2 =H
Embodiment 2
[0048] The synthesis of embodiment 2, (2a~2f)
[0049] Install a 250mL two-neck round bottom flask on an electromagnetic stirrer, and equip it with a water separator and a thermometer. Add 1mol of 5-methylfurfural, then add 1~1.2mol of diol or mercaptan or its derivatives and 100~150ml of solvent, 1~10g of solid catalyst, mix and pour into the reactor, and then install the upper water separator Reflux and divide water for 4 to 12 hours in a conventional method, remove the solvent, and distill under reduced pressure to obtain the following saturated five-membered heterocyclic compounds.
[0050]
[0051] 2a: X 1 =X 2 =O, R 1 = R 2 =H
[0052] 2b:X 1 =X 2 =O, R 1 =CH 3 , R 2 =H
[0053] 2c:X 1 =X 2 =O, R 1 =CH 2 Cl, R 2 =H
[0054] 2d:X 1 = S, X 2 =O,R 1 = R 2 =H
[0055] 2e:X 1 = S, X 2 =O, R 1 = R 2 =CH 3
[0056] 2f: X 1 =X 2 = S, R 1 = R 2 =H
Embodiment 3
[0057] The synthesis of embodiment 3, (3α~3f)
[0058] Install a 250mL two-neck round bottom flask on an electromagnetic stirrer, and equip it with a water separator and a thermometer. Add 1mol of 3-ethylthiobutyraldehyde, then add 1~1.2mol of diol or mercaptan or its derivatives and 100~150ml of solvent, 1~10g of solid catalyst, mix and pour into the reactor, and then install The water separator is refluxed and separated for 4 to 12 hours by a conventional method, the solvent is removed, and the vacuum distillation is carried out to obtain the following saturated five-membered heterocyclic compounds.
[0059]
[0060] 3a: X 1 =X 2 =O, R 1 = R 2 =H
[0061] 3b:X 1 =X 2 =O, R 1 =CH 3 , R 2 =H
[0062] 3c:X 1 =X 2 =O,R 1 =CH 2 Cl, R 2 =H
[0063] 3d:X 1 = S, X 2 =O,R 1 = R 2 =H
[0064] 3e: X 1 = S, X 2 =O,R 1 = R 2 =CH 3
[0065] 3f: X 1 =X 2 = S, R 1 = R 2 =H
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