Compositions and methods of delivery of pharmacological agents

a technology of pharmacological agents and compositions, applied in the field of compositions of pharmaceutical products, can solve the problems of unfavorable drug safety, undesirable side effects, venous irritation, burning and pain, etc., and achieve the effects of reducing one or more side effects of administration, and inhibiting microbial growth
US20050004002A1Inactive Publication Date: 2005-01-06ABRAXIS BIOSCI LLC
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
ABRAXIS BIOSCI LLC
Publication Date
2005-01-06
Estimated Expiration
Not applicable · inactive patent
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Abstract

The present invention relates to a pharmaceutical composition comprising a pharmaceutical agent and a pharmaceutically acceptable carrier, which carrier comprises a protein, for example, human serum albumin and / or deferoxamine. The human serum albumin is present in an amount effective to reduce one or more side effects associated with administration of the pharmaceutical composition. The invention also provides methods for reducing one or more side effects of administration of the pharmaceutical composition, methods for inhibiting microbial growth and oxidation in the pharmaceutical composition, and methods for enhancing transport and binding of a pharmaceutical agent to a cell.
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Description

CROSS-REFERENCE TO RELATED PATENT APPLICATIONS

[0001] This patent application claims the benefit of U.S. Provisional Patent Application No. 60 / 432,317 filed Dec. 9, 2002, U.S. Provisional Patent Application (Attorney Docket No. 225519) filed Dec. 3, 2003, U.S. Provisional Patent Application (Attorney Docket No. 225549) filed Dec. 4, 2003, and U.S. Provisional Patent Application (Attorney Docket No. 225585) filed Dec. 5, 2003.FIELD OF THE INVENTION

[0002] This invention pertains to pharmaceutical compositions comprising pharmaceutically active agents for parenteral or other internal use, which have the effect of reducing certain undesirable side effects upon administration when compared with available formulations of similar drugs. BACKGROUND OF THE INVENTION

[0003] It is well recognized that many drugs for parenteral use, especially those administered intravenously, cause undesirable side effects such as venous irritation, phlebitis, burning and pain on injection, venous thrombosis,...

Claims

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