Method and apparatus for identifying constituent signal components from a plurality of evoked physiological composite signals

a composite signal and signal component technology, applied in the field of medical equipment and methods, can solve the problems that the linear mixture model of ica is not suitable for spatially separated peripheral compound muscles and sensory nerve action potentials, and achieves the effect of improving diagnostic indices and improving the accuracy of electrodiagnostic parameter estimation
US20050283090A1Inactive Publication Date: 2005-12-22WELLS MARTIN D
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
WELLS MARTIN D
Publication Date
2005-12-22
Estimated Expiration
Not applicable · inactive patent

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Abstract

A novel application of independent component analysis (ICA) to data acquired by a single sensor. The technique exploits the unique relationship between multiple physiologic (source) and electronic (artifact) components in surface recorded sensory nerve action potential (SNAP) waveforms that are evoked by different activating magnitudes. A forward model of the SNAP is developed and used to test the approach on a simplified data simulation. The method is applied to experimental data and shown to be effective at separating artifact and source components and reconstructing artifact-free traces. A method of automated reconstruction for use within an expert system is also disclosed.
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Description

REFERENCE TO PENDING PRIOR PATENT APPLICATION

[0001] This patent application claims benefit of pending prior U.S. Provisional Patent Application Ser. No. 60 / 298,831, filed Jun. 18, 2001 by Martin D. Wells for METHODS FOR EXTRACTING OR SEPARATING MULTIPLE EVOKED PHYSIOLOGICAL SIGNAL COMPONENTS FROM RECORDINGS CONSISTING OF THEIR MIXTURES (Attorney's Docket No. NEURO-3 PROV), which patent application is hereby incorporated herein by reference.FIELD OF THE INVENTION

[0002] This invention relates to medical apparatus and methods in general, and more particularly to methods and apparatus for identifying constituent signal components from a plurality of evoked physiological composite signals. BACKGROUND OF THE INVENTION

[0003] Non-invasive peripheral nerve conduction studies (NCS) are an important tool in the diagnosis and assessment of neuromuscular injuries and pathologies. Electrical stimulation of a nerve bundle by surface electrodes produces impulses that travel in both the proximal ...

Claims

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