Dose packaging system for load-dose titration administration of a liquid formulation

Abstract

The invention generally relates to a dose packaging system for the administration of a liquid formulation to a patient requiring load-dose titration therapy of a pharmaceutically active drug, such as steroid therapy. More particularly, the invention relates to a dose packaging system for administering titration therapy of liquid formulations to a patient which eliminates the disadvantages that are associated with cups, dosing spoons, calibrated oral syringes and bottles.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS [0001] This application claims priority to and benefit under 35 U.S.C. § 119(e) of U.S. Provisional Application Ser. No. 60 / 783,401 filed Mar. 20, 2006, the disclosure of which is expressly incorporated herein by reference in its entirety.BACKGROUND [0002] 1. Field of the Invention [0003] The invention generally relates to a dose packaging system for the administration of a liquid formulation to a patient requiring load-dose titration therapy of a pharmaceutically active drug, such as steroid therapy. More particularly, the invention relates to a dose packaging system for administering titration therapy of liquid formulations to a patient which eliminates the disadvantages that are associated with cups, dosing spoons, calibrated oral syringes and bottles. [0004] 2. Related Art [0005] Administration of liquid medication is a common practice, especially among children, for a variety of conditions. While administration of liquid oral medication h...

AI Technical Summary

Benefits of technology

[0009] The invention satisfies the above needs by providing a dose packaging system including pre-filled ampoules for

Problems solved by technology

While administration of liquid oral medication has many benefits, there are drawbacks as well, which may vary the efficacy and safety of the medications.

This condition can also negatively affect children's academic performance because of doctor visits during school hours, lack of concentration while at school because of nighttime attacks, and decreased attentiveness or involvement at school because of the side effects of some medications.

There is no evidence that intravenous corticosteroids are any more effective than oral corticosteroids in children with an intact and functioning digestive tract.

Administering oral medications to children, however, is often very difficult.

However, there are several disadvantages associated with these dosing instruments: (1) the numbers on the sides of the dosing instruments are often small and difficult to read, which may result in the child receiving an inaccurate dose; (2) droppers tend drip, thus the liquid formulation must be administered quickly to the child otherwise, the child will not receive the proper dose; and (3) while dosage cup may be convenient for children who can drink from a cup, the dosage cup may spill.

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