Novel Melanocortin Receptor Templates, Peptides, and Use Thereof

a melanocortin receptor and template technology, applied in the field of new chimeric peptides and templates, can solve the problems of affecting the ability of people to interact socially with others, wreak havoc on an individual's mental health, and harmful physical health,
US20080146496A1Inactive Publication Date: 2008-06-19HASKELL LUEVANO CARRIE
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
HASKELL LUEVANO CARRIE
Publication Date
2008-06-19
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to novel chimeric peptides and templates containing a combination of antagonist and agonist endogenous ligand residues. In particular, the present invention relates to novel chimeric peptides and templates thereof based upon melanocortin agonist peptides and agouti related protein (AGRP). The present invention provides multifunctional chimeric peptides having specific bioactivity at melanocortin receptors and their use as drugs to treat various diseases and conditions.
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Description

CROSS-REFERENCE TO RELATED APPLICATIONS

[0001] This application is a divisional application of co-pending application Ser. No. 11 / 491,596, filed Jul. 24, 2006; which is a continuation of co-pending application U.S. Ser. No. 10 / 602,394, filed Jun. 23, 2003, now U.S. Pat. No. 7,084,111, which are incorporated by reference herein in their entirety.GOVERNMENT SUPPORT

[0002] This invention was made with government support under a grant awarded from the National Institutes of Health under grant numbers DK57080 and DK64250. The government has certain rights in the invention.FIELD OF THE INVENTION

[0003] The present invention relates to novel chimeric peptides and templates containing a combination of antagonist and agonist endogenous ligand residues. In particular, the present invention relates to novel chimeric peptides and templates thereof based upon melanocortin agonist peptides and agouti related protein (AGRP) antagonist peptide, and their use as drugs to treat various diseases and conditi...

Claims

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