Filter contamination control device
a technology of contamination control and filter, which is applied in the direction of specific use of bioreactors/fermenters, biomass after-treatment, biochemical apparatus and processes, etc., can solve the problems of liquid dripping and contamination of the arm, difficult to evaluate, and inability to provide accurate diagnostic assessment of collected samples
Inactive Publication Date: 2008-07-03
CYTYC CORP
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Benefits of technology
The fluid trap effectively reduces contamination, making the device more reliable and reducing the need for repeated cleaning, thereby enhancing the integrity of biological specimen collection and transfer systems.
Problems solved by technology
Because the sample may contain debris, blood, mucus and other obscuring artifacts, the test may be difficult to evaluate, and may not provide an accurate diagnostic assessment of the collected sample.
When the filter cartridge is moved and rotated, this liquid may drip and contaminate the arm, which is non-disposable.
First, some biological samples are very inconvenient, if not impossible, to re-harvest.
While it is highly inconvenient for a patient to repeat a pap smear, it is may not be possible to repeat a biopsy on a mole that has been removed to test for malignancy.
Second, for those situations where a second sample collection is not a viable option, chain of custody issues can have serious repercussions.
Such chain of custody issues can call into doubt entire batches of test results and, in the worst cases, all results from a clinical lab.
However, this alternative is difficult to implement in a fully automatic device and it is labor intensive.
Further, repeated cleaning reduces the life expectancy of the rubber o-rings sealing the interface.
Method used
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[0026]In the following description of the illustrated embodiments, it will be understood by those skilled in the art that the drawings and specific components thereof are not necessarily to scale, and that various structural changes may be made without departing from the scope or nature of the various embodiments.
[0027]Referring to FIGS. 1 and 2, a filter / container interface 10 of a biological specimen collection and transfer system 12 is shown. In this embodiment, the filter / container interface 10 includes a stem 14, air tight seals 16, a filter cartridge 18, and a sample container 20. The stem 14 is connected, with the air tight seals 16, to the filter cartridge 18. The stem 14, in turn, is connected to a vacuum source 11.
[0028]The filter cartridge 18 includes a tubular body 22 with a membrane 24 at a second end 26 and a first end 28 configured to connect to the stem 14. The second end 24 is configured to be submerged into a liquid 30 containing a biological specimen (not shown), ...
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A biological specimen filter, for use in a biological specimen collection and transfer system having a vacuum source, comprises a tubular body having an exterior surface, an interior chamber, a first end configured to couple to the vacuum source, and a second end having an opening in communication with the chamber, and a fluid trap extending around at least a portion of a circumference of the exterior surface of the tubular body and sized and shaped to catch fluid flowing along the exterior surface as the tubular body is inverted from a first position, in which the opening is submerged in a fluid source, to a second position, in which the opening is removed from the fluid source.
Description
FIELD OF INVENTION[0001]The present inventions generally relate to devices for collecting and transferring microscopic particles to prepare biological specimens, and more particularly, to devices for controlling contamination associated with such devices.DESCRIPTION OF RELATED ART[0002]Many medical diagnostic tests, such as pap smears, require a physician to collect cells by brushing and / or scraping a skin or mucous membrane in a target area with an instrument. The collected cells are typically smeared (“fixed”) onto a slide, and stained to facilitate examination under a microscope by a cytotechnologist and / or pathologist. For example, a pathologist may employ a polychrome technique, characterized by staining the nuclear part of the cells, to determine the presence of dysplasia or neoplasia. The pathologist may also apply a counter-stain for viewing the cytoplasm of the cells. Because the sample may contain debris, blood, mucus and other obscuring artifacts, the test may be difficul...
Claims
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IPC IPC(8): C12M1/00
CPCG01N1/24C12M33/14C12M33/02G01N2015/0088G01N2015/019
InventorTENNEY, DOUGLAS A.
OwnerCYTYC CORP