Method of Manufacturing Packaging Comprising Pharmaceutical Products

a manufacturing method and technology for pharmaceutical products, applied in the direction of packaging/bundling articles, medical devices, packaged goods, etc., can solve the problems of relatively cumbersome production methods and extremely complicated overall methods

Inactive Publication Date: 2008-11-06
UHLMANN PAC SYST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0016]By means of the additional step of introducing perforations into the bottom layer and into the sealing film between the wells, the possibility is obtained of being able to separate individual sections for specific administration times of specific days from the multi-day package.

Problems solved by technology

The above-mentioned production method is relatively cumbersome, however, because of the complicated mechanisms required and the double packaging step of the tablets.
The method is also critical from a contamination standpoint, because, when the tablets are pushed out by the plungers, tablet dust is created, which settles on the plungers and in the tub-like wells.
The overall method is extremely complicated.

Method used

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  • Method of Manufacturing Packaging Comprising Pharmaceutical Products
  • Method of Manufacturing Packaging Comprising Pharmaceutical Products
  • Method of Manufacturing Packaging Comprising Pharmaceutical Products

Examples

Experimental program
Comparison scheme
Effect test

first embodiment

[0029]A flow chart of the inventive method for producing the multi-day package is shown in FIG. 3.

[0030]First, wells 10 to hold the drugs are formed in a bottom layer 11 (step 32). For this purpose, the bottom layer 11 is pulled from a roll, possibly heated in a heating station, and then provided with the wells 10 in a following forming station.

[0031]Then a predetermined number of different drugs are arranged (step 34) in predetermined positions at various dispensing stations of the filling station. The steps to be carried out for this purpose in the case of the embodiment according to FIG. 3 are explained in the following.

[0032]First, in step 35, a base layer of considerable size in the longitudinal and transverse directions is formed, as a result of which a large number of supply-blister pockets 16 is obtained. For this purpose, the base layer is unwound from a roll, possibly heated in a heating station, and provided with the supply-blister pockets 16 in a forming station. Then th...

second embodiment

[0040]The arrangement 34 of a predetermined number of a drug in predetermined positions at a dispensing station of the filling device can also be carried out in accordance with a second embodiment, as can be seen from FIGS. 4 and 6.

[0041]In this case, the holders of a sorting plate 56, which are arranged in correspondence with the pattern of the wells 10 in the multi-day package, are filled with drugs. The individually controlled suction or gripper devices 50 can be arranged above the sorting plate 56 in correspondence with the pattern of the holders. This is especially effective when large numbers of these drugs are to be packed into each multi-day package. The placing of the drugs onto the sorting plate 56 is preferably accomplished by means of a vibrating chute. To ensure that all of the holders of the sorting plate 56 are filled, a brushing movement with a brush device 58 is then preferably carried out, which also takes care of removing excess tablets from the sorting plate 56.

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Abstract

The method for producing a multi-day package containing various drugs has the following steps: a bottom layer is formed with a plurality of wells arranged in a pattern; a predetermined number of different drugs is arranged in predetermined positions at various dispensing stations of a filling device; the desired number of drugs are picked in a controlled manner from their predetermined positions at each dispensing station by at least one movable suction or gripper device, and the drugs are deposited in the predetermined wells; and a sealing film is applied to the bottom layer to seal off the wells. In the course of this method, in at least one dispensing station several suction or gripper devices, which are arranged in correspondence with the pattern of the wells in the multi-day package and which travel parallel to each other, are actuated individually.

Description

CROSS REFERENCE TO RELATED APPLICATION[0001]This application claims priority based on European patent application EP 07 008 966.9, filed May 3, 2007.FIELD OF THE INVENTION[0002]The invention pertains to methods for producing multi-day packages which contain various drugs for several days and for several administration times.DESCRIPTION OF THE PRIOR ART[0003]The multiple blister pockets of conventional blister packs are intended to hold a single type of medicament. A device for filling these conventional blister packs is described in, for example, DE 199 26 893 C2.[0004]In the treatment of patients with chronic diseases, however, there is often room for improvement with respect to the patient's ability to take his or her medicaments consistently in accordance with the prescribed therapy. This is especially true when different sets of tablets must be taken at different times of day. To provide a memory aid which helps the patient take his or her medicaments correctly and also to ensur...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): B65B17/00B65B35/36B65B35/38B65B43/00
CPCA61J1/035A61J7/0084A61M2207/00B65B5/103B65B5/105B65B11/50
Inventor DROST, SIEGFRIEDFELK, GUNTERPFAU, GEORGBONGERS-AMBROSIUS, HANS-WERNERPRINZ, HEINOMERTENS, RICHARD
Owner UHLMANN PAC SYST
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