Reagents and methods for modulating cone photoreceptor activity

a technology of cone photoreceptors and receptors, applied in the field of cone cell gene therapy, can solve the problems of ineffective treatment of congenital vision disorders, inability to appropriately process inputs that were not present at birth, and inability to properly process inputs established during development. to achieve the effect of restoring visual capacity
US20120172419A1Inactive Publication Date: 2012-07-05MCW RES FOUND INC +1
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Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
MCW RES FOUND INC
Publication Date
2012-07-05
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention provides reagents and methods for modulating cone photoreceptor activity, and devices for assessment of cone photoreceptor activity.
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Description

RELATED APPLICATIONS

[0001] This application claims priority to U.S. Provisional Patent Application Ser. No. 61 / 242587 filed Sep. 15, 2009, incorporated by reference herein in its entirety.STATEMENT OF U.S. GOVERNMENT SUPPORT

[0002] This work was supported by the National Institutes of Health grants R01EY016861, R01EY11123, and P30EY01730. The U.S. government has certain rights in the invention.BACKGROUND

[0003] Classic visual deprivation experiments have led to the expectation that neural connections established during development would not appropriately process an input that was not present from birth. Therefore, it was believed that treatment of congenital vision disorders would be ineffective unless administered to the very young.SUMMARY OF THE INVENTION

[0004] In a first aspect, the present invention provides methods for cone cell gene therapy in a primate, comprising administering to the eye of a primate in need of cone cell gene therapy a recombinant gene delivery vector comprisin...

Claims

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