System, apparatus and method for material preparation and/or handling

Abstract

Oscillating angularly rotating a container containing a material may cause the material to be separate. Denser or heavier material may unexpectedly tend to collected relatively close to the axis of rotation, while less dense or light material may tend to collect relatively away from the axis of rotation. Oscillation along an arcuate path provides high lysing efficiency. Alternatively, a micromotor may drive an impeller removably received in a container. Lysing may be implemented in batch mode, flow-through stop or semi-batch mode, or flow-through continuous mode. Lysing particulate material may exceed material to be lysed or lysed material and / or air may be essentially eliminated from a chamber to increase lysing efficiency.

Description

TECHNICAL FIELD[0001]The present disclosure relates to the separation of matter, for example particles or other material in a suspension. The present disclosure also relates to lysing and in particular to systems, apparatus and methods to perform lysing of a material to be lysed using a lysing particulate material.BACKGROUND[0002]There are numerous applications that require the separation of material, for example particulate or other matter in suspension. One common approach is to employ a centrifuge to separate relatively heavier material from relatively light material. Centrifuges typical include a container to hold the material, a drive system including a motor and transmission or linkage coupled to rotate the container about a fixed axis of rotation. The material in the container separates based on density under centripetal acceleration, with denser or heavier material tending to collect at a perimeter relatively away from the axis of rotation and with the less dense or lighter ...

AI Technical Summary

Benefits of technology

The patent text discusses the need for more efficient and effective methods of separating materials. This can involve faster, more thorough separations or separations in a different manner. There is also a need for more efficient bead-based lysing apparatus and methods that can process small samples quickly and with greater thoroughness. These methods may require less lysing materials, reduce costs, and enable the processing of large quantities of small samples over time. The patent also mentions the need for small and portable lysing equipment that is affordable and robust enough for travel or harsh operating environments.

Problems solved by technology

These chemical approaches may adversely affect the resulting product, for example degrading the bio-products being released.

Consequently, chemical approaches may, in some instances, not be practical.

Such an approach may not achieve as high a lysis efficiency as may be required or desired for many applications.

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