Combination therapy of Anti-her3 antibodies

a technology of anti-her3 antibodies and conjugates, which is applied in the field of conjugation therapy of anti-her3 antibodies, can solve the problems of poor patient prognosis, correlates or associations of overexpression of egfr, and achieve the effect of inhibiting the dimerization of her2
US20160159912A1Inactive Publication Date: 2016-06-09F HOFFMANN LA ROCHE INC
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
F HOFFMANN LA ROCHE INC
Publication Date
2016-06-09
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to the combination therapy of anti-HER3 antibodies with certain anti-HER antibodies.
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Description

CROSS REFERENCE TO RELATED APPLICATIONS

[0001] This application is a continuation of U.S. application Ser. No. 14 / 151,626 filed on Jan. 9, 2014, now U.S. Pat. No. 9,180,185, which claims priority to European Patent Application No. EP 13151076.0 filed Jan. 11, 2013, the disclosures of both of which are incorporated herein by reference in their entirety.SEQUENCE LISTING

[0002] The present application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Jan. 7, 2014, is named P5733US_ST25.txt and is 54,072 bytes in size.FIELD OF THE INVENTION

[0003] The present invention relates to the combination therapy of anti-HER3 antibodies with certain anti-HER antibodies.BACKGROUND OF THE INVENTION

[0004] Human HER3 (ErbB-3, ERBB3, c-erbB-3,c-erbB3, receptor tyrosine-protein kinase erbB-3, SEQ ID NO: 17) encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosi...

Claims

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