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Bioresorbable scaffold for treatment of bifurcation lesion

a bioresorbable and scaffold technology, applied in the direction of prosthesis, blood vessels, catheters, etc., can solve the problems of reducing flow or other negative effects, failure of metallic stents, and particularly of bioresorbable polymer stents, so as to improve mechanical properties of formed substrates, reduce flexibility, and impede navigation

Inactive Publication Date: 2017-08-31
RAZMODICS LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The resulting stents exhibit improved mechanical properties, such as high ductility and radial strength, allowing for secure expansion and self-expansion within vessels without fracturing, while minimizing obstruction of side branches during bifurcation treatments.

Problems solved by technology

However, the stent that has been placed in the main vessel may obstruct part of the opening to the side branch and cause flow reduction or other negative effects.
However, enlarging the open cells of an already expanded stent may form or create cracks in the stent struts leading to failure for metallic stents and particularly for bioresorbable polymeric stents.

Method used

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  • Bioresorbable scaffold for treatment of bifurcation lesion
  • Bioresorbable scaffold for treatment of bifurcation lesion
  • Bioresorbable scaffold for treatment of bifurcation lesion

Examples

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Embodiment Construction

[0043]In manufacturing implantable devices from polymeric materials such as biocompatible and / or biodegradable polymers, a number of casting processes described herein may be utilized to develop substrates, e.g. cylindrically shaped substrates, having a relatively high level of geometric precision and mechanical strength. These polymeric substrates can then be machined using any number of processes (e.g., high-speed laser sources, mechanical machining, etc.) to create devices such as stents having a variety of geometries for implantation within a patient, such as the peripheral or coronary vasculature, etc.

[0044]An example of such a casting process is to utilize a dip-coating process. The utilization of dip-coating to create a polymeric substrate having such desirable characteristics results in substrates which are able to retain the inherent properties of the starting materials. This in turn results in substrates having a relatively high radial strength which is mostly retained thr...

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Abstract

Bioresorbable scaffolds for treatment of bifurcation lesion are described herein. Generally, an expandable scaffold may be fabricated from a high molecular weight isotropic PLLA material, wherein the scaffold incorporates one or more strain relief features which are configured to allow side branch treatment.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application is a continuation of U.S. patent application Ser. No. 14 / 334,562 filed Jul. 17, 2014, which claims the benefit of priority to U.S. Prov. App. 61 / 866,859 filed Aug. 16, 2013, each of which is incorporated herein by reference in its entirety.FIELD OF THE INVENTION[0002]The present invention relates generally to stent or scaffold delivery and deployment methods and apparatus. More particularly, the present invention relates to methods and apparatus for bioresorbable scaffolds which may be used for the treatment of bifurcation lesions.BACKGROUND OF THE INVENTION[0003]In treating diseased vessels, particularly blood vessels which have one or more side branches extending from a main vessel, difficulties may arise when implanting stents at these junctions to treat lesions. For instance, when implanting a stent along the main vessel, the openings to the side branches may become restricted by the stent walls. Although open cells a...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61F2/06A61L31/06A61M25/02
CPCA61F2210/0076A61L31/06A61F2/915A61F2/958A61F2/954A61F2/856A61F2210/0004A61L31/04A61F2240/001A61F2002/91575C08L67/04
Inventor RAMZIPOOR, KAMALLEE, CHANG Y.
Owner RAZMODICS LLC
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