Denture adhesive

a technology of adhesives and dentures, applied in the field of denture adhesives, can solve the problems of easy dissociation of "cross-links" and inconvenient use, and the denture does not always fit perfectly

Inactive Publication Date: 2000-12-26
BLOCK DRUG CO INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Despite diligent efforts by dental professionals and designers of dental prostheses, dentures do not always fit perfectly.
Over time, even well-fitting dentures can become ill-fitting due to natural shrinkage and changes in the gum or mucous tissues.
Such a "cross-link" may be very easily dissociated in the presence of water.
One problem with denture adhesive copolymers, particularly MVE/MA copolymers, is that covalent cross-linking is not an attractive approach

Method used

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Examples

Experimental program
Comparison scheme
Effect test

examples 10-17

A partial calcium salt of poly methylvinyl ether / maleic acid was prepared by adding 74.87 g GANTREZ AN 169 to 1250 ml. of vigorously mixed deionized water. Then L-Lysine monohydrate 0.24 g was added to the mixture, and the resulting mixture was held at room temperature for 30 minutes with continuous mixing to form a slurry solution.

24.89 g of calcium hydroxide was added to the slurry solution and the mixture was heated to 85-90 degrees C. The temperature was maintained at 85-90 degrees C for 2 hours with continuous mixing. The solution of the partial salt was discharged into trays (while maintaining batch temperature and mixing speed), and the solution was heated in an 85 degree C oven until dry.

The salt was milled and used to make a denture adhesive cream formula. This salt is 0.3 Lysine-70 Ca GANTREZ Salt. Using different amounts of lysine and metal oxides, different percentages of substitution of Lysine-GANTREZ Salts were prepared and used to make denture adhesive creams by combi...

examples 18-19

A 0.5 percent substitution lysine, 40 percent substitution Zinc, 20 percent substitution Magnesium, and 10 percent substitution Sodium methylvinyl ether maleic acid copolymer salt was prepared by adding 75.93 9 of GANTREZ AN 169 to 1,000 ml. of vigorously mixed deionized water. Then 0.40 9 L-Lysine monohydrate was added to the mixture, and the resulting mixture was held at room temperature for 30 minutes with continuous mixing.

A solution of 250 ml of deionized water containing 15.85 g zinc oxide, 3.93 g magnesium oxide and 3.90 g sodium hydroxide was added gradually to the lysine GANTREZ AN slurry and the mixture was heated to 85-90 degrees C and held at that temperature for 2 hours with continuous mixing. The solution of the partial salt was discharged into trays (while maintaining batch temperature and mixing speed), and the salt was heated at 85 degrees C until dry. The dry salt was milled and used to make a denture adhesive cream formula.

A small consumer test showed that the den...

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Abstract

A denture adhesive comprising a copolymer salt at least partially cross-linked by lysine, histidine, arginine, nontoxic derivatives or family members of lysine, histidine or arginine and mixtures thereof.

Description

1. Field of the InventionThe invention relates to denture adhesives and to processes for making and using denture adhesives.2. Description of Related ArtDentures are substitutes for missing teeth and serve as a replacement for all or some of the teeth found in the oral cavity. Despite diligent efforts by dental professionals and designers of dental prostheses, dentures do not always fit perfectly. Over time, even well-fitting dentures can become ill-fitting due to natural shrinkage and changes in the gum or mucous tissues. Therefore, adherent creams, liquids or powders are often used to secure or temporarily fix dentures within the mouth.There are a number of desirable attributes of such a denture adhesive composition. The denture adhesive should develop a high degree of tack upon contact with saliva so that the dentures can be held in place as soon as they are seated in the mouth. It is also highly desirable that the saliva hydrated adhesive be spread over the denture-mucosa interf...

Claims

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Application Information

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IPC IPC(8): A61K6/00C08F8/30C08F8/00C09J135/00C09J135/08C09J129/10
CPCC08F8/30C09J135/08A61K6/0067A61K6/0061A61K6/0026C08L77/04C08L33/08C08L35/08C08L2666/36A61K6/66A61K6/69A61K6/35A61K6/00
Inventor AHN, HYUNG-KOOKGASMAN, ROBERT C.WONG, EDDIE
Owner BLOCK DRUG CO INC
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