The invention discloses a special 
chitosan derivative-based water-free 
hand washing liquid for children, and a preparation method thereof, wherein the special 
chitosan derivative-based water-free 
hand washing liquid comprises the following raw materials by weight: 0.1-5 parts of a 
chitosan derivative, 0.01-1 part of a 
viscosity modifier, 1-10 parts of glycerin, 0.01-1 part of a 
skin-care agent, 0.01-0.5 part of a surfactant, and 100 parts of deionized water. According to the present invention, the water-free 
hand washing liquid with advantages of safety, no harm to 
human body, 
environmental protection and efficient 
antibacterial property is prepared by using the 
chitosan derivative macromolecule having the antibacterial 
function group as the active substance; and the water-free hand washing liquid designed for the children 
skin has the reasonable formula, can form the protective film on the child 
hand surface after the use, can kill a variety of 
pathogenic bacteria in children, and has characteristics of strong antibacterial ability, 
long acting time, no color, no 
odor, no 
toxicity, no irritating, smoothness and comfort after the use, no requirement of 
water rinsing, convenient use, and convenient carrying.