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Medicine composite and process for preparing the same

A composition and drug technology, applied in the field of medicine, can solve the problems of many side effects, limited effect, inaccuracy and the like

Active Publication Date: 2007-12-12
YUNNAN PANLONG YUNHAI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many types of synthetic drugs and biological agents for the treatment of this disease, but so far, due to problems such as limited and inaccurate effects and many side effects, the western medicine industry has not yet found an ideal drug for the prevention and treatment of this disease

Method used

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Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0025] Experimental Example 1 Pharmaceutical composition capsule of the present invention (Panlongyun brand Limian Lirong Capsule) improves sleep effect experiment

[0026] The recommended human dose of the test substance is 3.0g / 60kg.bw Panlongyun Limian Lirong Capsules per day. The equivalent dose in mice is 10 times the recommended human dose. The low (0.25g / kg.bw), medium (0.50g / kg.bw), and high (1.50g / kg.bw) doses are respectively 5 times, 10 times and 30 times the recommended dose for the human body. The method of intragastric administration was adopted, the control group was administered with distilled water, and each dose group was given different doses of the test substance.

[0027] After the mice in each group were given the test substance for four weeks, various indexes were measured.

[0028] 1. Experimental process

[0029] 1. Direct sleep test

[0030] Observe whether the animals appear sleep phenomenon after being given different doses of the test substance...

experiment example 2

[0061] Experimental Example 2 Composition Capsules of the present invention (Panlongyun Brand Limian Lirong Capsule) Cosmetology (Removing Chloasma) Function Human Food Trial Experiment

[0062] 1. Objects and methods:

[0063] 1. Subject: Panlongyun Limian Lirong Capsules

[0064] 2. Subjects: 30 subjects aged 18-65 with chloasma were selected on a voluntary basis.

[0065] Diagnostic criteria: Yellowish-brown spots can be seen on the head and face with the naked eye, mostly on the cheeks, cheeks, forehead, nose, and around the lips, without symptoms such as pain and itching.

[0066] Inclusion criteria: All voluntary subjects with chloasma, who have passed the physical examination, can have a food trial observation.

[0067] Excluder Criteria:

[0068] (1) People under the age of 18 or over 65 years old, pregnant or breastfeeding women, and those who are allergic to this health care product.

[0069] (2) Patients with serious primary diseases such as heart, liver, kidney...

Embodiment 1

[0123] Example 1 Pharmaceutical composition tablet of the present invention

[0124] Gastrodia elata 2kg Panax notoginseng 2kg Schisandra 1.5kg Suanzaoren 1.5kg

[0125] Poria cocos 1kg Angelica dahurica 1kg Pearl 0.5kg Vitamin C 400g

[0126] Vitamin E powder (contains vitamin E 50%) 200g

[0127] Make 6000 tablets according to conventional methods, take it for patients with insomnia and chloasma, 2 times a day, take 3 tablets each time,

[0128] After determination, the total saponin contained in each tablet is 11.2mg / g calculated as ginsenoside Re; vitamin E is 30.4mg / g; vitamin C is 20.2g / 100g; calcium is 5.3g / 100g.

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PUM

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Abstract

The invention discloses a medicinal composition for improving sleeping and beauty treatment, which is prepared from gastrodia tuber, notoginseng, schisandra fruit, wild jujuba seeds, poria cocos, dahurian angelica root, pearl powder, vitamin C and vitamin E. The invention also discloses the process for preparing capsules from the composition.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a pharmaceutical composition with beautifying and sleep-improving effects and a preparation method thereof, belonging to the technical field of medicine. Background technique [0002] Chloasma refers to the chloasma pigmentation spots mainly limited to the cheeks and forehead, which is also called "Dai dark spots" and "liver spots" in traditional Chinese medicine. [0003] The disease is common in healthy women, and occurs from puberty to menopause, especially in the second to fifth months of pregnancy, and gradually disappears during menstruation after childbirth, which may be related to the increase in the level of progesterone in the body. It has been studied that during pregnancy, the secretion of MSH increases, the serum copper increases, and the sulfhydryl value in the blood decreases. These changes may make the function of melanocytes active....

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61K36/725A61K36/57A61K36/258A61K36/232A61K36/076A61K35/56A61K9/48A61K9/28A61K9/16A61K9/107A61P25/20A61P17/00A61K35/618
Inventor 焦家良曾立品杜波
Owner YUNNAN PANLONG YUNHAI PHARMA