New process for making animal medicine madumycin ammonium, ivermection or dikezhuli premixed agent
A technology of maduramycin ammonium and ivermectin, which is applied in the directions of anti-infective drugs, drug combinations, pharmaceutical formulations, etc., can solve the problems of difficulty for manufacturers, increased cost, low production efficiency, etc., and achieves avoiding the danger of decomposition, The effect of improved dispersion performance and improved production efficiency
Inactive Publication Date: 2008-12-03
CHINA ANIMAL HUSBANDRY IND +1
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AI Technical Summary
Problems solved by technology
But this technology has following shortcoming: 1, organic solvent volatilizes in the air and can pollute the environment
In addition, organic solvents, especially non-volatile organic solvents, will contaminate products, and the contaminated products will cause certain harm to animals; organic solvents will also contaminate mixing equipment, making it unfavorable for equipment cleaning
All of these make it difficult for manufacturers to pass the GMP certification for national drug manufacturers; and because of the use of organic solvents, the cost increases. For example, 25 kg of solvent benzyl alcohol is required to produce 1 ton of products, costing 1650 yuan ; 2. When heating and drying, raw materials with poor thermal stability may be decomposed; 3. There are many production steps and the production efficiency is not high
Method used
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Experimental program
Comparison scheme
Effect test
Embodiment 1
[0022] 10 kg of maduramycin ammonium raw powder is directly compressed into granules with a dry granulator, and the particle size of the granules is 30-80 mesh.
[0023] The prepared ammonium maduracin granules and corncob granules with a particle size of 30-80 mesh are put into a 2000-liter mixer, and after uniform stirring, the finished ammonium maduracin premix is obtained.
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Abstract
The present invention provides a process of preparing veterinary medicine preblend preparation made up by using madumycin ammonium and ivermectin or dikezhuli.
Description
technical field [0001] The present invention relates to a kind of process of manufacturing veterinary drug premix, more specifically, the present invention relates to a kind of manufacturing veterinary drug maduramicin ammonium (Maduramicin Ammonium), ivermectin (Ivermectin) or diclazuril (Diclazuril) Premix process Background technique [0002] As we all know, chicken coccidiosis can cause growth and development stagnation of chickens, reduce egg production (thus reducing feed remuneration), and even cause chickens to die in severe cases. When chickens are raised intensively, coccidiosis is more likely to occur, so the prevention and control of chicken coccidiosis is a problem that needs to be seriously solved today. [0003] It has been found that the antibiotic veterinary drug maduracin ammonium of polyether is an effective drug for preventing and treating chicken coccidiosis; however, the amount of maduramycin ammonium that chickens should eat by feed should be appropri...
Claims
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IPC IPC(8): A61K31/765A61K31/7048A61K9/16A61P33/00A23K1/16A23K20/10A23K20/121A23K20/195
Inventor 朱高群周镇赵晓萌
Owner CHINA ANIMAL HUSBANDRY IND