Chinese-medicinal composition for treating cough asthma

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition, can solve the problems of poor drug stability, inability to long-term clinical application, difficult quality control and the like

Inactive Publication Date: 2009-12-02
NAT INST FOR THE CONTROL OF PHARMA & BIOLOGICAL PROD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] There are many medicines used to treat diseases such as cough and asthma. There are chemical medicines and traditional Chinese medicines. Chemical medicines have good curative effects but often have large side effects. In clinical application, most of them are due to insignificant curative effect, rough preparation, difficult quality control, poor drug stability, or because ephedra, opium poppy and other poisonous and anesthetic drugs are added to the prescription, and long-term use leads to drug dependence, or because the addition of The chemical or hormonal components that have the effect of relieving cough and relieving asthma will produce side effects such as drug resistance, so that they cannot be used in long-term clinical use. This shows that the pure Chinese medicine preparation in the true sense (does not contain dependent poisons and anesthetics and chemicals or hormones) ingredients) are still relatively weak in the cough and asthma treatment market
The characteristics of good curative effect and low side effects of traditional Chinese medicine in the treatment of diseases have not been fully reflected. There are reasons for the formulation of the traditional Chinese medicine, and there are also reasons for the craftsmanship. Definite, significant and safe pure Chinese herbal medicine for treating cough and asthma diseases

Method used

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  • Chinese-medicinal composition for treating cough asthma
  • Chinese-medicinal composition for treating cough asthma
  • Chinese-medicinal composition for treating cough asthma

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0171] The prescription of the composition of the present invention:

[0172] Angelica volatile oil 7%; lampstand leaf extract 93%. The total weight of the composition composed of the volatile oil of angelica sinensis and the extract of the leaves of the lampstand is 100%.

[0173] Extraction of the volatile oil of Angelica sinensis: take the medicinal materials of Angelica sinensis and prepare by distillation to obtain the volatile oil of Angelica sinensis;

[0174] Extraction of the extract of the leaf of the lampstand: take the medicinal material of the leaf of the lampstand, add 95% ethanol to reflux twice, each time for 2 hours, filter, combine the filtrate, recover the ethanol to a certain amount, add 2 times the amount of water, stir, and stand for 24 hours. Filtrate, concentrate the filtrate, and spray-dry it into a powder to obtain the extract of the leaves of the lampstand;

[0175] Mix the above-mentioned volatile oil of angelica sinensis and the extract of the le...

Embodiment 2

[0197] Prescription: Angelica volatile oil 25%; lampstand leaf extract 75%. The total weight of the composition composed of the volatile oil of angelica sinensis and the extract of the leaves of the lampstand is 100%.

[0198] Tablet: (1) take angelica medicinal material, adopt the method for supercritical extraction of carbon dioxide to prepare, and obtain angelica volatile oil;

[0199] (2) Take the medicinal material of Dengtai leaves, add water and decoct twice, 2 hours each time, combine the decoction, filter, concentrate the filtrate to a relative density of 1.3, add ethanol to an alcohol content of 65%, let it stand for 24 hours, and take the supernatant Ethanol is recovered from the liquid, spray-dried into powder, and the extract of the leaves of the lampstand is obtained;

[0200] (3) mixing the extracts obtained in the above (1) and (2);

[0201] (4) Add conventional doses and types of tablet adjuvants, and compress to obtain the tablet of the present invention. ...

Embodiment 3

[0211] Prescription: 5% Angelica volatile oil; 95% lampstand leaf extract. The total weight of the composition composed of the volatile oil of angelica sinensis and the extract of the leaves of the lampstand is 100%.

[0212] Tablet: (1) take Chinese angelica medicinal material, adopt the method for steam distillation to prepare, and obtain the volatile oil of Chinese angelica;

[0213] (2) Take the medicinal material of the lampstand leaf, add 75% ethanol to reflux twice, each time for 2 hours, filter, combine the filtrate, recover the ethanol to a certain amount, add 2 times the amount of water, stir, stand for 24 hours, filter, and concentrate the filtrate , spray-dried into powder to obtain the extract of the leaves of the lampstand;

[0214] (3) mixing the extracts obtained in the above (1) and (2);

[0215] (4) Add conventional tablet excipients and compress into tablets.

[0216] Capsules: after the step (3) of mixing the above extracts, add fillers such as starch, a...

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PUM

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Abstract

The present invention relates to a traditional Chinese medicine composition and a medicine containing the composition, as well as a preparation method and application of the medicine, wherein the components of the composition include 5-90% extract of Dengtai leaves and 95-10% volatile oil of Angelica sinensis, wherein the The above-mentioned extract of leaves of the lampstand contains indole alkaloids accounting for 1-90% of the total weight of the extract, and the indole alkaloids contains 0.1-80% of the total weight of the extract; The traditional Chinese medicine composition can be used to treat diseases such as cough and asthma.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, which is composed of angelica volatile oil and lampstand leaf extract, which is mainly used for treating diseases such as cough and asthma. Background technique [0002] Cough and asthma are common respiratory diseases with many causes. [0003] Cough is one of the most common symptoms in the respiratory system. It is a protective measure of the human body and is beneficial to the body. When the respiratory mucosa is stimulated by foreign bodies, inflammation, secretions or allergic factors, it will be caused reflexively. Cough helps to eliminate foreign bodies or secretions that invade the respiratory tract from the outside and eliminate respiratory irritation factors. However, if it affects work and rest due to frequent irritating cough, it loses its protective significance. Sudden coughs are mostly caused by acute upper respiratory tract inflammation (especially those caused by i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/28A61P11/06A61P11/14
Inventor 林瑞超王钢力戴忠姚令文刘燕
Owner NAT INST FOR THE CONTROL OF PHARMA & BIOLOGICAL PROD
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