Sperm suspensions for sorting into x or y chromosome-bearing enriched populations

A suspension and sperm technology, applied in the preservation of human or animal bodies, the preparation and application of test samples, etc., can solve the problems of reduced forward motility
CN101014700AActive Publication Date: 2007-08-08INGURAN LLC
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
INGURAN LLC
Publication Date
2007-08-08

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Abstract

Sperm cell suspensions comprising a motility inhibitor are disclosed. The cells contained in such suspensions tend to have a greater capacity for enduring the various process steps typically associated with the sorting of sperm cells into gender enriched populations, thereby resulting in post-sort compositions with an increased number of viable or motile sperm. Processes for forming such cell suspensions, as well as processes for staining sperm cells, are also disclosed.
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Description

field of invention

[0001] The present invention generally relates to methods for sorting sperm cells. More specifically, the present invention relates to the preparation of a suspension of sperm cells with reduced motility relative to ejaculated sperm, more specifically temporarily reduced motility; said suspension may be used, for example, to sort sperm cells bearing X or Method for Enriching Sperm Cell Populations for the Y Chromosome. Background of the invention

[0002] Fertilization of animals by artificial insemination (AI) and embryo transfer after in vitro fertilization is a well-established technology. In the livestock industry, there are clear advantages in being able to influence reproductive outcome so that offspring possess one or more desired characteristics. For example, in the dairy industry, if the offspring can be pre-selected in favor of females and the production of cows can be guaranteed, it will bring economic benefits. Separating sperm into enriched...

Claims

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