8 results about "Motile sperms" patented technology

A system and method for improving sperm selection during in vitro fertilization (IVF) procedures includes a sperm containment apparatus equipped with a capture system designed to isolate motile sperm as they respond to the presence of a retrieval instrument within the sperm solution. As more motile and potentially healthier sperm move away from the retrieval instrument, they are selectively corralled within certain regions of the apparatus. The capture mechanism may include various structures, such as a barrier member including one or more passageways which direct sperm movement. By isolating sperm based on their motility, this invention enhances the selection process, improving the chances of successful fertilization with higher-quality sperm. This system provides a more efficient and targeted approach to sperm retrieval compared to conventional methods.

A device for filtering out non-functional sperm and separating motile sperm may include a main channel having a flow direction from a first end toward a second end of the main channel. The device may include a buffer inlet in fluid communication with the first end of the main channel. The apparatus may include a collection chamber in fluid communication with the second end of the main channel. The device may include a secondary channel in fluid communication with the collection chamber on a downstream side. The apparatus may include a waste chamber in fluid communication with the secondary channel on a downstream side.

The application relates to the field of animal breeding technology, in particular to a method and system for detecting total live sperm count of a cow and application. The method comprises the following steps: based on the genome version ARS-UCD1.2, the methylation level of a region such as chr17:62205563-63205744 of a to-be-detected cow is detected; the detection result is compared with a reference standard, and the total live sperm count of the to-be-detected cow is obtained; the reference standard is obtained based on GWAS correlation data of the total live sperm count and the methylation level of a reference cow group in the region of chr17:62205563-63205744. A region significantly related to the total live sperm count of the cow is obtained through research, early identification of the total live sperm count of the cow can be realized by detecting the methylation level of the region, and this has important significance in the field of animal phenotype identification.

A sperm sorting device is suitable for sorting a plurality of motile sperm from a semen sample, and includes a base and a first sorter positioned on the base. The base includes a receiving space defined by a bottom wall and a surrounding wall. The first sorter includes a first kit and a first permeable membrane. The first kit has a first sleeve for being placed into the receiving space. The first sleeve has a first inner sleeve surface and a first outer sleeve surface. The first permeable membrane is fixed to the first sleeve. The first permeable membrane and the inner wall surface of the bottom wall and the surrounding wall define a first sample receiving chamber for receiving the semen sample. In this way, the motile sperm can naturally swim upward and pass through the first permeable membrane, and the quality of sperm sorting can be improved.

This invention discloses a barrel-shaped sperm selection device for selecting highly motile sperm from semen samples. The device includes a container with a porous membrane inside, which divides the interior of the container into an initial chamber and a filtration chamber. This allows the semen sample to move through the porous membrane to the filtration chamber, achieving the selection purpose. The advantages of this invention are: the overall barrel shape of the device, with the porous membrane arranged on a hub along the axial direction of the cylindrical container to form inner and outer cavities, simplifies the structure and optimizes the principle, greatly reducing the requirements for molds and processes. The barrel-shaped structure with inner and outer cavities prevents semen overflow even when the semen sample volume is too large; and prevents reduced selection rates due to air bubbles even when the semen sample volume is too small.

The invention relates to a microfluidic device, method, and use for the continuous, label-free isolation of motile, morphologically normal spermatozoa from semen samples This invention offers a gentle, reliable, and efficient platform for sperm selection, serving as an alternative to centrifugation-based techniques in ART laboratories. By maintaining the structural and genetic integrity of sperm, it improves fertilization success, embryo quality, and pregnancy outcomes. The platform also reduces variability between technicians and limits exposure to reactive oxygen species (ROS), ensuring consistent clinical performance. Beyond its application in fertility treatments, the system can be used as a diagnostic tool to assess sperm motility disorders, susceptibility to oxidative stress, and DNA fragmentation dynamics under different environmental conditions or drug exposures.

A method for enhancing artificial insemination (AI) in mammals, particularly bovine livestock, uses a specialized aqueous mastic solution to substantially increase conception success rates from conventional 60-65% to about 95%. The solution comprises ionic minerals including magnesium chloride, calcium chloride, sodium, potassium, and an emulsion of milled mastic gum (Pistacia lentiscus, preferably Chios Mastiha, particulates 15-40 μm) dissolved in water sourced from inland saltwater bodies such as the Great Salt Lake, delivering approximately 72 ionic and trace minerals. The process involves: preparing the uterus by depositing the solution via syringe to maintain pH at 7.35-7.45 and eliminate bacteria; washing donor semen in the solution to isolate healthy, motile sperm and remove debris / reactive elements; and depositing the washed semen directly into the uterus during ovulation, confirmed via luteinizing hormone detection, ultrasound, or chorionic gonadotropin induction.

The invention relates to a microfluidic device, method, and use for the continuous, label-free isolation of motile, morphologically normal spermatozoa from semen samples This invention offers a gentle, reliable, and efficient platform for sperm selection, serving as an alternative to centrifugation-based techniques in ART laboratories. By maintaining the structural and genetic integrity of sperm, it improves fertilization success, embryo quality, and pregnancy outcomes. The platform also reduces variability between technicians and limits exposure to reactive oxygen species (ROS), ensuring consistent clinical performance. Beyond its application in fertility treatments, the system can be used as a diagnostic tool to assess sperm motility disorders, susceptibility to oxidative stress, and DNA fragmentation dynamics under different environmental conditions or drug exposures.