Reagent box for accurately discriminating catfish and large-mouth catfish and discrimination method
A technology for identifying catfish and largemouth catfish, which can be used in biochemical equipment and methods, microbial determination/inspection, etc., and can solve the problems of distinction and difficulty in correct identification.
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Embodiment 1
[0037] The kit for identifying catfish and largemouth catfish can be used 100 times, and its composition is as follows:
[0038] (a) DNA extraction reagents, including
[0039] Reagent 1, 40ml, its composition is: 10mmol / L Tris-HCl, pH8.0; 2mmol / L EDTA, pH8.0; 0.4mol / L NaCl, 1% SDS;
[0040] Reagent 2, 0.8ml, its composition is: proteinase K, 20mg / mL;
[0041] Reagent 3, 30 ml, its composition is: sodium chloride, 6mol / L;
[0042] Reagent 4: 30ml isopropanol (analytical pure);
[0043] Reagent 5: 100ml 70% ethanol.
[0044] (b) polymerase chain reaction reagents: including reaction premix reagent 6 and reagent 7;
[0045] Reagent 6, containing 100 parts of the following components (the number in parentheses is the volume of 1 part, and the total amount of 100 parts is 2450 μl): 10 times polymerase chain reaction buffer (containing MgCl 2 15mM) (2.5μl), specific primers NS (0.5μl (10μM)) and NA (0.5μl (10μM)) (please biotechnology companies (such as Shanghai Sangong, Hands...
Embodiment 2
[0061] 1. Take 50 mg of fish fins, cut them into pieces, and add 400 μl of reagent 1;
[0062] 2. Add 10 μl of Reagent 2, and bathe in water at 60°C for about 2 hours until there are no particles in the solution;
[0063] 3. Add 300 μl of reagent 3, shake and mix for 30 seconds, then centrifuge at 10,000×g for 30 minutes, and transfer the supernatant to a new centrifuge tube;
[0064] 4. Add an equal volume of reagent 4, place at -20°C for 1 hour, then centrifuge at 10,000×g for 15 minutes, discard the supernatant;
[0065] 5. Wash the precipitate with 1ml of Reagent 5, centrifuge at 10,000×g for 5min, dry in the air, dissolve in sterilized double distilled water, and obtain the DNA extraction solution;
[0066] 6. PCR amplification: take 1 μl of DNA as the template for PCR amplification; mix 23.875 μl of reagent 6 with 0.125 of reagent 7; melt at 94°C for 3 minutes on a thermal cycler; then denature at 94°C for 30 seconds, Renature for 30 seconds, extend at 72°C for 45 seco...
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