Angiocardiopathy treating traditional Chinese medicine and the preparing technology thereof

A cardiovascular and disease technology, which is applied in the field of traditional Chinese medicine for the treatment of cardiovascular disease and its preparation technology, and can solve the problems of western medicine with large toxic and side effects and many adverse reactions.

Inactive Publication Date: 2007-12-05
深圳市韦泓药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] There are many chemical drugs currently on the market for the treatment of cardiovascular and cerebrovascular diseases, but because cardiovascular and cerebrovascular diseases need to be taken for a long time,

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Get 250g of safflower yellow and 200ml of mannitol, add 70% (V / V) sterile water for injection of the theoretical dosing amount, stir and dissolve, add 0.05% of the dosing amount of activated carbon for needles, filter to remove carbon, Use sodium bicarbonate to adjust the pH value to 5.5, replenish the liquid to 2000ml, sterilize the filling, pre-cool to -40°C, vacuumize after 3.5 hours, raise the temperature of the frozen product to -25°C, continue for 10 hours, and then cool the sample temperature Rise to 18°C ​​and vacuum dry for 6 hours.

Embodiment 2

[0018] Get 180g of safflower yellow and 220ml of mannitol, add 70% (V / V) sterile water for injection of the theoretical dosing amount, stir and dissolve, add 0.02% of the dosing amount of active carbon for needles, filter to remove carbon, Use disodium hydrogen phosphate to adjust the pH value to 6.0, add liquid to 2000ml, sterilize and fill, pre-cool to -35°C, vacuumize after 5 hours, raise the temperature of the frozen product to -15°C, continue for 12 hours, and then make the sample The temperature was raised to 22°C, and vacuum-dried for 5 hours.

Embodiment 3

[0020] Get 64g of safflower yellow and 16 sodium chloride, add 70% (V / V) sterile water for injection of the theoretical dosing volume, stir and dissolve, add 0.08% of the dosing volume of activated carbon for needles, filter to remove carbon , use citric acid to adjust the pH value to 5.0, add liquid to 2000ml, sterilize and fill, pre-cool to -45°C, vacuumize after 2 hours, raise the temperature of the frozen product to -20°C, continue for 8 hours, and then make the sample The temperature was raised to 15°C, and vacuum-dried for 5 hours.

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PUM

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Abstract

The present invention is one kind of freeze dried Chinese medicine powder for injection for treating cardiac and cerebral vascular diseases and its preparation process, and features that the freeze dried Chinese medicine powder is composition of safflower uranidin as the effective component, freeze dried powder supporting agent and pH regulator. The freeze dried Chinese medicine powder for injection possessing functions of promoting blood circulation, dredging meridian, eliminating blood stasis and relieving pain is used in treating coronary heart disease, angina pectoris and other cardiac and cerebral vascular diseases.

Description

field of invention [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a freeze-dried powder for injection of a traditional Chinese medicine for treating cardiovascular diseases and a preparation method thereof, in particular to taking the active ingredient safflower yellow of the traditional Chinese medicine safflower as the active ingredient and a freeze-dried powder support agent, The freeze-dried powder composed of a combination of pH regulators has the effects of promoting blood circulation, dredging menstruation, removing blood stasis and relieving pain, and is used to treat cardiovascular and cerebrovascular diseases such as coronary heart disease and angina pectoris. Background technique [0002] Chest obstruction and heart pain syndrome in traditional Chinese medicine, coronary heart pain, angina pectoris and myocardial infarction in Western medicine are common clinical diseases and one of the top ten diseases that endanger human...

Claims

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Application Information

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IPC IPC(8): A61K31/352A61K9/19A61P9/10
Inventor 江韦
Owner 深圳市韦泓药业有限公司
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