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Medicine for treating glaucoma and method for preparing the same

A glaucoma and drug technology, applied in the field of drugs for the treatment of glaucoma diseases, can solve problems such as difficulty, difficulty in meeting the intensity and duration of the effect of lowering intraocular pressure, limitations of glaucoma, etc.

Inactive Publication Date: 2008-01-30
THE SECOND HOSPITAL OF SHANXI MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above treatment methods for glaucoma are difficult to meet the intensity and duration of the effect of lowering intraocular pressure, especially for glaucoma with normal intraocular pressure, it is more difficult to reduce normal intraocular pressure than to reduce elevated intraocular pressure
Therefore, the above-mentioned existing drugs or combinations thereof still have limitations in the treatment of glaucoma

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Take 800g Schisandra chinensis, 400g Gentiana, 200g Corydalis Corydalis, 200g Platycodon grandiflorum, and 100g wine rhubarb, pick out impurities, wash, screen and dry, mix well, and grind into 80 mesh fine powder for later use.

[0036] Cassia 500g, Plantago 200g, Chrysanthemum 400g, Horsetail 200g, Tribulus terrestris 500g, Scutellaria baicalensis 300g, Gardenia 300g, Nepeta 200g, Fangfeng 200g, Notopterygium 200g, Curcuma 200g, Bupleurum 200g, Chuanxiong 200g, Divine Comedy 300g , add 300g of malt, 300g of hawthorn to 10L water for decoction, add the same amount of water to decoct the dregs of medicine twice, decoct for 60 minutes each for the first and second time, decoct for 30 minutes for the third time, and combine the decoction for 3 times, Filter and concentrate into a thick paste with a relative density of 1.20-1.22 (60°C).

[0037] Add the above-mentioned drug fine powder into the thick ointment, mix evenly, and after drying at 60°C, pulverize into a 100-mesh...

Embodiment 2

[0039] Take 750g of schisandra, 350g of gentian, 150g of Corydalis 150g, 150g of Platycodon grandiflora, 150g of wine rhubarb, pick out all impurities, wash, screen and dry, mix well, and grind into 80 mesh fine powder for later use.

[0040] Cassia 600g, Plantago 150g, Chrysanthemum 450g, Horsetail 250g, Tribulus terrestris 450g, Scutellaria baicalensis 200g, Gardenia 200g, Nepeta 150g, Fangfeng 150g, Notopterygium 150g, Curcuma 150g, Bupleurum 150g, Chuanxiong 150g, Divine Comedy 200g , 200g of malt, 200g of hawthorn were added to 8L of water for decoction, the dregs of the medicine were added to the same amount of water and decocted twice, the first and second decoction were each for 60 minutes, the third decoction was for 45 minutes, and the three decoctions were combined. Filter and concentrate into a thick paste with a relative density of 1.20-1.22 (60°C).

[0041] Add the above-mentioned drug fine powder into the thick ointment, mix evenly, and after drying at 60°C, pul...

Embodiment 3

[0043] Take 850g Schisandra chinensis, 400g Gentiana, 300g Corydalis Corydalis, 300g Platycodon grandiflorum, and 80g wine rhubarb, pick out impurities, wash, screen and dry, mix well, and grind into 100 mesh fine powder for later use.

[0044] Cassia 550g, Plantago 250g, Chrysanthemum 350g, Horsetail 300g, Tribulus terrestris 600g, Scutellaria baicalensis 250g, Gardenia 250g, Nepeta 300g, Fangfeng 300g, Notopterygium 300g, Curcuma 300g, Bupleurum 300g, Chuanxiong 300g, Divine Comedy 250g , 250g of malt and 250g of hawthorn were added to 10L of water for decoction, and the dregs of the medicine were added to the same amount of water for decoction twice, the first and second decoctions were each for 50 minutes, the third decoction was for 30 minutes, and the three decoctions were combined. Filter and concentrate into a thick paste with a relative density of 1.20-1.22 (60°C).

[0045] Take the above drug fine powder and add it to the thick ointment, mix evenly, and after drying ...

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Abstract

The present invention relates to a drug for treating glaucoma, the Chinese magnoliavine fruit, Chinese gentian, yanhusuo, platycodon root and rhubarb which is stir-fried with wine are mixed and smashed into the fine powder, the cassia seed, plantain seed, chrysanthemum, common scouring rush herb, puncturevine caltrop fruit, baical skullcap root, gardenia, fineleaf schizonepeta herb, divaricate saposhnikovia root and other medicines are added with water for boiling, then the medicines are filtered and condensed into the thick paste, and the medicine powder is added for even mixing, finally the mixture is smashed and filled in the capsule and the product is obtained. The drug of the present invention has the effects of soothing liver, clearing fire, clearing heat, improving eyesight, decreasing pupil size, stopping pain and lowering intraocular pressure, which is applicable to the treatment of glaucoma with the liver channel repletion heat type and the liver qi stagnancy type; the present invention has the advantages of easy administration, accurate efficacy and no toxicity or side effects etc.; the total effective rate can reach 93.3 percent through the clinical efficacy observations of 90 cases of patients with glaucoma.

Description

technical field [0001] The invention relates to a medicine for treating glaucoma, in particular to a medicine for treating glaucoma prepared from traditional Chinese medicines. The invention also relates to a preparation method of the medicine. Background technique [0002] Glaucoma refers to an ophthalmic disease in which intraocular pressure increases due to various causes, which damages the optic nerve and causes it to atrophy, resulting in abnormal visual field and gradually reduced vision. The clinical manifestations of glaucoma are relatively hidden and progress slowly, and there are generally no symptoms in the early stage. When the intraocular pressure rises, individual patients may feel eye swelling, foggy vision, rainbow vision and slight headache. Once the optic nerve atrophies, it cannot recover, and if left untreated, glaucoma can often lead to blindness. Even if the treatment is successful, it is only at the level of maintaining the status quo, and it is dif...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/48A61P27/06
Inventor 孔繁森赵生芳张京平郝敏李育民樊水琴谢桂凤
Owner THE SECOND HOSPITAL OF SHANXI MEDICAL UNIV
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