Chinese goldthread colla corii asini decoction oral preparation and preparing method thereof
An oral preparation, the technology of donkey-hide gelatin soup, which is applied in the field of medicine, can solve the problems of inaccurate dosage, large dosage of traditional Chinese medicine decoction, and inability to commercialize it.
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Embodiment 1
[0038] Example 1: Preparation method of Coptidis Ejiao Decoction Extract 1
[0039] Prescription: Coptidis 3 grams, Scutellaria baicalensis 9 grams, peony 9 grams, donkey-hide gelatin 9 grams, chicken yellow 2 pieces
[0040] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, first add Coptidis Rhizoma, Scutellaria Baicalensis, and Peony to 6-10 times the amount of water, soak for 2-4 hours, heat and extract 2-3 times, and combine the extracts; water The extract is left to stand for 12-48 hours, filtered to take the supernatant, and concentrated under reduced pressure to obtain the extract as a water extract. Add melted donkey-hide gelatin to the water extract, cool it, then add chicken yellow and dry it, about 25.1g .
Embodiment 2
[0041] Example 2: Preparation method of Coptidis Ejiao Decoction Extract 2
[0042] Prescription: Coptidis 6g, Scutellaria baicalensis 6g, peony 12g, donkey-hide gelatin 12g, chicken yellow 2 pieces
[0043] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, first add Coptis chinensis, Scutellaria baicalensis, and peony to 8-12 times the amount of water, soak for 2-4 hours, heat and extract 2-3 times, and combine the extracts; water The extract was left to stand for 12-48 hours, filtered to take the supernatant, and spray-dried to obtain a dry powder as a water extract, which was made by adding melted donkey-hide gelatin to the water extract, cooling, and then adding chicken yellow and drying, about 30.2g.
Embodiment 3
[0044] Example 3: Preparation method of oral solid preparation of Huanglian Ejiao Decoction
[0045] (1) Preparation of Huanglian Ejiao Decoction Granules
[0046] prescription:
[0047] Coptis Ejiao Decoction Extract 1 10-90%
[0048] Starch 5.0-70%
[0049] Dextrin 2.0-20%
[0050] Xylitol 5.0-20%
[0051] Methyl sorbate 0.001-2.0%
[0052] Preferred Prescription:
[0053] Coptidis Ejiao Decoction Extract 1 25.1g
[0054] Starch 5.0g
[0055] Dextrin 10.0g
[0056] Xylitol 5.0g
[0057] Methyl sorbate 0.005g
[0058] Preparation method: Prepare Chaihuanglian Ejiao Decoction extract according to the method in Example 1, add prescription amount of auxiliary materials to make granules according to conventional methods, dry at low temperature, and pack.
[0059] (2) Preparation of Huanglian Ejiao Decoction Pills
[0060] prescription:
[0061] Coptidis Ejiao Decoction Extract 2 30.2g
[0062] Starch 10g
[0063] Magnesium stearate 0.1g
[0064] Dextrin 5g
[006...
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