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Chinese goldthread colla corii asini decoction oral preparation and preparing method thereof

An oral preparation, the technology of donkey-hide gelatin soup, which is applied in the field of medicine, can solve the problems of inaccurate dosage, large dosage of traditional Chinese medicine decoction, and inability to commercialize it.

Inactive Publication Date: 2008-07-30
苏州世林医药技术发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] The ancient Coptidis Ejiao Decoction only has decoction, which needs to be decocted and taken after purchasing decoction pieces. It is very inconvenient to carry and take it. After research, we have made modern oral preparations of traditional Chinese medicine through quantitative control of index components. The product dosage is accurate, the quality is stable, and it is convenient to take. , suitable for large-scale commercial production, overcomes the shortcomings of traditional Chinese medicine decoctions such as large dosage, inaccurate dosage, inconvenient carrying and taking, and inability to commercialize, and is convenient for clinical treatment and home use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Example 1: Preparation method of Coptidis Ejiao Decoction Extract 1

[0039] Prescription: Coptidis 3 grams, Scutellaria baicalensis 9 grams, peony 9 grams, donkey-hide gelatin 9 grams, chicken yellow 2 pieces

[0040] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, first add Coptidis Rhizoma, Scutellaria Baicalensis, and Peony to 6-10 times the amount of water, soak for 2-4 hours, heat and extract 2-3 times, and combine the extracts; water The extract is left to stand for 12-48 hours, filtered to take the supernatant, and concentrated under reduced pressure to obtain the extract as a water extract. Add melted donkey-hide gelatin to the water extract, cool it, then add chicken yellow and dry it, about 25.1g .

Embodiment 2

[0041] Example 2: Preparation method of Coptidis Ejiao Decoction Extract 2

[0042] Prescription: Coptidis 6g, Scutellaria baicalensis 6g, peony 12g, donkey-hide gelatin 12g, chicken yellow 2 pieces

[0043] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, first add Coptis chinensis, Scutellaria baicalensis, and peony to 8-12 times the amount of water, soak for 2-4 hours, heat and extract 2-3 times, and combine the extracts; water The extract was left to stand for 12-48 hours, filtered to take the supernatant, and spray-dried to obtain a dry powder as a water extract, which was made by adding melted donkey-hide gelatin to the water extract, cooling, and then adding chicken yellow and drying, about 30.2g.

Embodiment 3

[0044] Example 3: Preparation method of oral solid preparation of Huanglian Ejiao Decoction

[0045] (1) Preparation of Huanglian Ejiao Decoction Granules

[0046] prescription:

[0047] Coptis Ejiao Decoction Extract 1 10-90%

[0048] Starch 5.0-70%

[0049] Dextrin 2.0-20%

[0050] Xylitol 5.0-20%

[0051] Methyl sorbate 0.001-2.0%

[0052] Preferred Prescription:

[0053] Coptidis Ejiao Decoction Extract 1 25.1g

[0054] Starch 5.0g

[0055] Dextrin 10.0g

[0056] Xylitol 5.0g

[0057] Methyl sorbate 0.005g

[0058] Preparation method: Prepare Chaihuanglian Ejiao Decoction extract according to the method in Example 1, add prescription amount of auxiliary materials to make granules according to conventional methods, dry at low temperature, and pack.

[0059] (2) Preparation of Huanglian Ejiao Decoction Pills

[0060] prescription:

[0061] Coptidis Ejiao Decoction Extract 2 30.2g

[0062] Starch 10g

[0063] Magnesium stearate 0.1g

[0064] Dextrin 5g

[006...

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PUM

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Abstract

The invention relates to a medical oral preparation of coptis chinensis donkey hide gelatin soup, which is prepared with five traditional herbs such as the coptis chinensis mainly for treating the insomnia of yin deficiency and fire excess and heart-kidney imbalance, and a preparation method thereof; according to conventional processes, the preparation is prepared with the extracts mixture of coptis chinensis, scutellaria, herbaceous peony, egg yolk and donkey hide gelation as raw materials, and pharmaceutically acceptable carriers or excipients as substrates; the invention has the effects of yin-enriching and fire-downbearing and fidget-relieving and nerve-calming, mainly cures the yin deficiency and fire excess and the insomnia of heart-kidney imbalance; the long clinical application of the prescription shows that the invention has good effects for neurasthenia and anxiety neurosis.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to an oral medicine preparation for treating insomnia caused by yin deficiency and hyperactivity of fire and incompatibility between the heart and the kidney and a preparation method thereof, in particular to an oral medicine taking the extract of the traditional Chinese medicine formula of Huanglian Ejiao Decoction as the active ingredient of the medicine. preparation. Background technique [0002] "Huanglian Ejiao Decoction" was created in "Treatise on Febrile Diseases" by Zhang Zhongjing in the late Eastern Han Dynasty. Yin reducing fire, relieving restlessness and calming the nerves, mainly treating insomnia syndrome of yin deficiency and hyperactivity of fire, heart-kidney disharmony. The long-term clinical application of the prescription shows that it has a good curative effect on neurasthenia and anxiety neurosis, and has wide application, and no obvious toxic and side effect...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61K9/48A61K9/16A61K9/10A61K47/38A61K47/34A61K47/32A61K47/22A61P25/20A61P25/22A61K35/36A61K35/54A61K47/10A61K47/26
Inventor 张文芳
Owner 苏州世林医药技术发展有限公司
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