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Medicament composition for treating hereditary ataxia and preparation method thereof

An ataxia, hereditary technology, applied in the field of traditional Chinese medicine compositions, can solve problems such as no effective treatment method

Inactive Publication Date: 2008-09-24
TIANKE RENXIANG TECH BEIJING
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Method used

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Examples

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Effect test

Embodiment 1

[0036] Embodiment 1: Chinese medicine composition granule of the present invention

[0037] (1) 180g of oysters and 250g of salvia miltiorrhiza are crushed into fine powder for later use;

[0038] (2) Anemarrhena 210g, Codonopsis 230g, Astragalus 130g, Rehmannia glutinosa 160g, Atractylodes macrocephala 260g, Achyranthes bidentata 130g, Clematis 180g, Danpi 210g, Eucommia 160g, Cuscuta 80g, Polygonatum 110g, Donkey-hide gelatin 160g, Caulis Spatholobus 160g, add water and decoct Boil twice, 2 hours each time, filter, combine the filtrate, let it stand for 48 hours, take the supernatant, concentrate under reduced pressure to a thick paste with a relative density of 1.20 (60°C), add the above fine powder and clear paste, and dry , crushed into fine powder, added 400g of lactose, 800g of dextrin, mixed evenly, sieved, wet granulated with 75% ethanol, dried, and packed into bags.

Embodiment 2

[0039] Embodiment 2: Chinese medicine composition capsule of the present invention

[0040] (1) 180g of oysters and 250g of salvia miltiorrhiza are crushed into fine powder for later use;

[0041] (2) Anemarrhena 210g, Codonopsis 230g, Astragalus 130g, Rehmannia glutinosa 160g, Atractylodes macrocephala 260g, Achyranthes bidentata 130g, Clematis 180g, Danpi 210g, Eucommia 160g, Cuscuta 80g, Polygonatum 110g, Donkey-hide gelatin 160g, Caulis Spatholobus 160g plus 8 Double the water and decoct twice, 2 hours each time, filter, combine the filtrates, let stand for 48 hours, take the supernatant, concentrate under reduced pressure to a thick paste with a relative density of 1.20 (60°C), add the above fine powder, and dry , crushed into fine powder, add 600g of dextrin, mix well, and put it into an empty capsule.

Embodiment 3

[0042] Embodiment 3: Chinese medicine composition tablet of the present invention

[0043] (1) 180g of oysters and 250g of salvia miltiorrhiza are crushed into fine powder for later use;

[0044] (2) Anemarrhena 210g, Codonopsis 230g, Astragalus 130g, Rehmannia glutinosa 160g, Atractylodes macrocephala 260g, Achyranthes bidentata 130g, Clematis 180g, Danpi 210g, Eucommia 160g, Cuscuta 80g, Polygonatum 110g, Donkey-hide gelatin 160g, Caulis Spatholobus 160g plus 8 Double the water and decoct twice, 2 hours each time, filter, combine the filtrates, let stand for 48 hours, take the supernatant, concentrate under reduced pressure to a thick paste with a relative density of 1.20 (60°C), add the above fine powder and clear water The paste is dried, crushed into fine powder, added with 300 g of starch, 200 g of microcrystalline cellulose, wet granulated with 70% 7 alcohol, compressed into tablets, and coated.

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PUM

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Abstract

The invention relates to a drug composition for curing hereditary ataxia. The drug composition is made of rehmannia glutinosa, rhizoma anemarrhenae, atractylis ovata, achyranthes, Clematis chinensis, root-bark of tree peony, radix codonopsitis, eucommia bark, common dodder, sealwort, colla corii asini, oyster, salvia miltiorrhiza, milk veteh, caulis spatholobi and / or a medically acceptable carrier. The invention also relates to a method for preparing the drug composition. The drug composition has the functions for tonifying the kidney and spleen, replenishing essence and brain, nourishing liver and calming wind, strengthening tendons and bones, etc., and is used for curing the symptoms of gait instability, swaying walking, nystagmus and asophia, etc. caused by the hereditary ataxia.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a medicine combination for treating hereditary ataxia and a preparation method thereof. Background technique [0002] Hereditary ataxia is a group of progressive degenerative diseases of the nervous system with prominent symptoms of ataxia and distance discrimination. Although it can be divided into three types according to the morning and evening of its onset, they all have common characteristics such as unsteady gait, walking swing, nystagmus, slurred pronunciation, and slow disease progression. The etiology of this disease is unknown so far, most of which are hereditary. The disease mostly involves the cerebellum, spinal cord and peripheral nervous system. Modern medicine has no effective treatment method except physical therapy. [0003] Hereditary ataxias are classified according to the type of ataxia: [0004] 1. Spinal type: (1) Friedreich type ataxia: [...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61K9/16A61K9/20A61K9/48A61P25/28A61K35/56A61K35/36A61K35/618
Inventor 王丽娟
Owner TIANKE RENXIANG TECH BEIJING
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