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Harmful bacterium control agent containing bacillus thuringiensis

A technology of Bacillus thuringiensis and Bacillus aureus, which is applied in the field of food, feed, and pharmaceuticals containing it, can solve the problems of no confirmed effect and safety, no research on prevention and treatment of pathogenic infection, and achieve an improved balance and inhibition proliferating effect

Inactive Publication Date: 2008-11-19
IDEMITSU KOSAN CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it is only shown here that Bacillus thuringiensis has insecticidal activity against nematodes isolated from the intestines of animals, and the effect and safety when it is actually orally fed to animals such as humans have not been confirmed.
[0011] That is, up to now, there has been no research on the use of drugs containing Bacillus thuringiensis to prevent and treat infectious diseases caused by pathogenic bacteria, or to inhibit intestinal intestinal infection by ingesting foods containing Bacillus thuringiensis or feeding animals with feed containing Bacillus thuringiensis. Proliferation of existing harmful bacteria, improvement of the balance of intestinal flora, prevention and treatment of infectious diseases

Method used

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  • Harmful bacterium control agent containing bacillus thuringiensis
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  • Harmful bacterium control agent containing bacillus thuringiensis

Examples

Experimental program
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Effect test

Embodiment

[0088] (1) Bile acid tolerance and anaerobic tests

[0089] 35 g of ordinary agar medium "Nitsui" (manufactured by Nissui Pharmaceutical Co., Ltd.) was added to 1,000 ml of deionized water and sterilized in an autoclave. After cooling to 45°C after sterilization, add bile powder (manufactured by Oxgall, manufactured by Difco) that was filtered and sterilized with a cellulose mixed ester membrane filter (0.45 μm in pore size, manufactured by Advantec Toyo Co., Ltd.), and the concentration of added bile powder was prepared. 0.3% by mass, 1% by mass and 3% by mass of ordinary agar plate medium.

[0090] Each of BGSC 4A3, BGSC 4D1, BGSC 4J4, and BGSC 4Q7 belonging to Bacillus thuringiensis was inoculated on a plain agar plate medium (1,000 ml of deionized water, 35 g of "Nitsui") to which no bile powder was added, and cultured at 37°C overnight. After culturing, bacterial cells were isolated from colonies formed on the plate medium, and were inoculated with a sterilized inoculati...

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PUM

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Abstract

Through suppression of the multiplication of pathogenic bacteria and inactivation of bacterial self-induced factors, the balance of intestinal flora is improved to thereby promote regulation of animal intestinal functions and enable prevention / treatment of infection induced by such pathogenic bacteria. Accordingly, a pharmaceutical containing Bacillus thuringiensis is administered to animals, and animals are caused to ingest a food or feed containing Bacillus thuringiensis.

Description

technical field [0001] The present invention relates to a harmful fungus control agent containing Bacillus thuringiensis, and medicines, food and feed containing the same. Background technique [0002] The microflora of the gastrointestinal tract play many extremely important roles in maintaining the function of the gastrointestinal tract and the physiological health of the whole body. Probiotic therapy shows the active use of microorganisms that are beneficial to health. Probiotics survive to reach the host's intestines, where they enhance the intestinal microflora and aid in digestive activity. In addition, the effects and properties of these probiotics such as "bacterial antagonism", "bacterial interference", "barrier effect", "hindering retention", "competitive exclusion (competitive exclusion)", etc., can improve the intestinal microbial flora. Balance and inhibit the proliferation of harmful systemic microorganisms. Since this kind of probiotics cannot constantly fo...

Claims

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Application Information

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IPC IPC(8): A61K35/74A01N63/00A23K1/16A23L1/30A61P1/10A61P31/04A61P43/00C12N1/20C12R1/07A23K10/18A23L33/135A61K35/742
CPCY02A50/30
Inventor 望月正己
Owner IDEMITSU KOSAN CO LTD
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