Process for preparing cyclodextrin

Abstract

The invention discloses a method for producing cyclodextrin, which belongs to the cyclodextrin production technical field. 15 percent of starch milk is prepared and stirred for 30 to 120 minutes at a medium temperature of between 60 and 90 DEG C, then the temperature is adjusted to 65 DEG C, cyclodextrin glucanotransferase is added, an enzyme-adding mode is to add at the beginning of a transformation reaction, or the cyclodextrin glucanotransferase is added for a few times when the transformation reaction is performed for 0, 2, 4 and 6h, the transformation reaction time is 8 hours, the prior mode is used to adjust a pH value during the transformation process, the pH value is controlled to between 6 and 9, and beta-cyclodextrin is produced by adopting a crystallization means after the filtration; and no organic solvent is added during the reaction process. The method utilizes native starch as a substrate without zymohydrolysis, and has low production cost and simple operation; no organic solvent is added, so a product, namely the cyclodextrin has no problem of residual organic solvent and no application limitation; compared with the prior non-solvent method of zymohydrolysis first and then transformation, the transformation rate is greatly improved.

Description

A kind of production method of cyclodextrin technical field The invention discloses a method for producing cyclodextrin, which is a method for producing cyclodextrin in a solvent-free method by using starch as a raw material to increase the conversion rate of β-cyclodextrin through mild heat treatment, and belongs to the technical field of cyclodextrin production. Background technique Cyclodextrins, also known as Scharding dextrins, consist of glucose units joined in a ring by α-1,4 linkages. Alpha, beta, and gamma cyclodextrins have 6, 7, and 8 glucose units, respectively. Cyclodextrin has the ability to form complexes with other compounds, so it is widely used in many fields such as food, medicine, and chemical industry. In China, the production of β-cyclodextrin has a history of more than ten years. At present, the domestic production of cyclodextrin adopts the organic solvent method, which has the advantage of high conversion rate, but the organic solvent is usually...

AI Technical Summary

Problems solved by technology

At present, in the traditional process, starch is usually liquefied first, and small molecular sugars are produced during the liquefaction process, which inhibits the progress of the cyclization reaction, thus reducing the conversion rate of cyclodextrin.