Use of garlic volatile oil in preparing medicine for preventing and treating septicemic bordetella bacilli

Abstract

The invention discloses a novel purpose of garlic volatile oil, in particular to an application of the garlic volatile oil in the preparation of a medicine for preventing and curing septica Bordetella. The experiments show that the minimum inhibitory concentration of the garlic volatile oil to the septica Bordetella is 125 mug / ml and the minimum bactericidal concentration is 250 Mug / mL.

Description

technical field [0001] The invention relates to the field of medicine, in particular to the new application of garlic volatile oil in the field of medicine. Background technique [0002] Bordetella is a group of strictly aerobic, non-fermentative, Gram-negative, non-spore-forming bacteria that grows slowly on Bauer-Jinger agar, forms bulges, has pili and capsules, and is β-hemolytic and toxic The I-phase colony of the force, each species has a close genetic relationship, and is a strict parasite and pathogenic bacterium in the respiratory tract of humans or warm-blooded animals. [0003] Bordetella septica is widely distributed in mammals throughout the world. Domestic animals from which this bacteria has been isolated include pigs, dogs, cats, horses, cattle, sheep, and goats; experimental animals include rabbits, guinea pigs, mice, rats, hamsters, and monkeys; wild animals include rats, ferrets, hedgehogs, raccoons, Foxes, skunks, koala bears and chinchillas. It causes ...

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Problems solved by technology

[0025] In recent years, a large number of basic studies have shown that garlic volatile oil has different degrees of inhibitory effects on Salmonella typhi, Orphan cholerae, Pseudomonas aeruginosa, Shigella dysenteriae, Staphylococcus aureus, Escherichia coli, Bacillus subtilis and Bacillus cereus , but its antibacterial effect on Bordetella septica has not been reported

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