Novel use of betelnut and extract thereof in preparing anti-AIDS medicament
An anti-AIDS and extract technology, applied in antiviral agents, pharmaceutical formulations, plant raw materials, etc., can solve problems such as unseen literature reports and patent disclosures, achieve low side effects, control the number of HIV viruses, and increase the number of immune cells. Effect
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Embodiment 1
[0042] Take 3 kg of betel nut fruit, extract it three times with 95% for 7, 5, and 3 days respectively, recover the solvent and concentrate to obtain extract A. Take 150 g of A, disperse with 500 mL of water, extract with petroleum ether, ethyl acetate and n-butanol, and extract 4 times respectively. Recover the solvent and concentrate to obtain AC (12 grams) and AD (28 grams) respectively, take 15 grams of AD and add 15 grams of medicinal starch, mix well, then mix well with 30 grams of dextrin, add ethanol (50%) in an appropriate amount to make soft material. Granulate through a 16-mesh nylon sieve, dry at 60°C, pass the dry granules through a 16-mesh sieve for granulation, add 5 grams of magnesium stearate, mix evenly, and press into tablets.
Embodiment 2
[0044] Take 4 kg of betel nut fruit, extract it three times with 95% for 7, 6, and 3 days respectively, recover the solvent and concentrate to obtain extract A. Take 200 grams of A, disperse with 500 mL of water, extract with petroleum ether, ethyl acetate and n-butanol, and extract 4 times respectively. Recover the solvent and concentrate to obtain extract AC (20 grams) and AD (40 grams) respectively, take 20 grams of AC and add 20 grams of medicinal starch, mix well, then mix with 40 grams of dextrin, add ethanol (50%) in an appropriate amount to make soft material. Granulate through a 16-mesh nylon sieve, dry at 60°C, pass the dry granules through a 16-mesh sieve for granulation, add 7 grams of magnesium stearate, mix evenly, and press into tablets.
Embodiment 3
[0046]Take 8 kg of betel nut fruit, extract it three times with 95% for 6, 5, and 4 days respectively, recover the solvent and concentrate to obtain extract A. Take 400 g of A, disperse with 1 L of water, extract with petroleum ether, ethyl acetate and n-butanol, and extract 4 times respectively. The solvent is recovered and concentrated to obtain extracts AC (40 g) and AD (80 g), respectively. Take 20 g of AC and AD, mix them evenly, add 60 g of medicinal starch, and fill them into capsules.
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