Use of aqueous extract of Trametes robiniophila Murr. in preparing medicament

A technology of water extract and Huaear fungus, which is applied in the direction of pharmaceutical formulations, antineoplastic drugs, drug combinations, etc., can solve other applications in the treatment of gastrointestinal cancer, breast cancer, lung cancer, and pancreatic cancer, which have not been reported. And other issues

Active Publication Date: 2009-05-27
QIDONG GAITIANLI MEDICINES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Huaier granules have the functions of strengthening the body, promoting blood circulation and eliminating diseases, and are mainly used for the treatment of liver cancer. There are also reports on the application in the treatment of gastrointestinal cancer, breast cancer, lung cancer, and pancreatic cancer. , endometrial cancer, vulvar cancer, prostate cancer, parotid gland cancer, thyroid cancer, salivary gland cancer, skin cancer, nasopharyngeal cancer, tongue cancer, oral cavity cancer, laryngeal cancer, brain tumor, gallbladder cancer, kidney cancer, gum cancer, testicular cancer Cancer, penile cancer, multiple myeloma, and malignant melanoma have not been reported

Method used

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  • Use of aqueous extract of Trametes robiniophila Murr. in preparing medicament
  • Use of aqueous extract of Trametes robiniophila Murr. in preparing medicament

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Preparation of extracts

[0039] (1) Take 1100g of fungus of Huai Er, add water to decoct, add 7 times the amount of water for the first time, boil for 6 hours, filter, and extract for later use;

[0040] (2) Add 5 times the amount of water for the second and third times respectively, boil for 6 hours, and filter;

[0041] (3) Combine three extracts and concentrate under reduced pressure to a clear paste with a relative density of 1.35-1.40 (55°C).

Embodiment 2

[0043] Preparation of Huaier Granules

[0044] Mix the clear paste obtained in Example 1 with sucrose, dextrin, soluble starch and flavoring agent in an appropriate amount, granulate, dry, and sieve to prepare 1000 g of Huaier granules.

Embodiment 3

[0046] Clinical Trials

[0047] 1 Materials and methods

[0048] 1.1 Test drug:

[0049]1, the prepared Huaier granule of embodiment 2.

[0050] 2. Drugs used in the control group:

[0051] Drugs purchased from

[0052] Carboplatin Yangzijiang Pharmaceutical Group Co., Ltd.

[0053] Cisplatin Jiangsu Hansoh Pharmaceutical Co., Ltd.

[0054] Pingyangmycin Zhejiang Hisun Pharmaceutical Co., Ltd.

[0055] Bleomycin Zhejiang Hisun Pharmaceutical Co., Ltd.

[0056] Adriamycin (Daunorubicin) Zhejiang Hisun Pharmaceutical Co., Ltd.

[0057] Mitomycin Zhejiang Hisun Pharmaceutical Co., Ltd.

[0058] Epirubicin Pfizer Pharmaceuticals (Wuxi) Co., Ltd.

[0059] Vincristine Sulfate Yangzhou Aosaikang Pharmaceutical Co., Ltd.

[0060] Vindesine Sulfate Hangzhou Minsheng Pharmaceutical Group Co., Ltd.

[0061] Methotrexate Shanghai Pharmaceutical (Group) Co., Ltd. Hualian Pharmaceutical Factory

[0062] Paclitaxel Yangzijiang Pharmaceutical Group Co., Ltd.

[0063] Cyclophospha...

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Abstract

The invention discloses a usage of Jew ear fungal aqueous extract in the preparation of a drug for curing tumors, wherein, the tumors include cervical cancer, ovarian cancer, carcinoma of endometrium, vulva cancer, prostate cancer, parotid gland, thyroid cancer, salivary gland cancer, skin cancer, nasopharyngeal carcinoma, tongue cancer, oral cavity cancer, carcinoma of larynx, encephaloma, carcinoma of gallbladder, renal carcinoma, gingival carcinoma, testicular cancer, penile cancer, multiple myeloma and / or malignant melanoma.

Description

technical field [0001] The invention relates to the field of plant extracts, in particular to the new application of the water extract of Huaier fungus. Background technique [0002] Huaier granule is a granule (granule) prepared by extracting the fungus of the medicinal material Huaier (approval number: Z20000108). Huaier granules have the functions of strengthening the body, promoting blood circulation and eliminating diseases, and are mainly used for the treatment of liver cancer. There are also reports on the application in the treatment of gastrointestinal cancer, breast cancer, lung cancer, and pancreatic cancer. , endometrial cancer, vulvar cancer, prostate cancer, parotid gland cancer, thyroid cancer, salivary gland cancer, skin cancer, nasopharyngeal cancer, tongue cancer, oral cavity cancer, laryngeal cancer, brain tumor, gallbladder cancer, kidney cancer, gum cancer, testicular cancer Cancer, penile cancer, multiple myeloma, and malignant melanoma have not been r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/06A61K9/08A61K9/10A61K9/14A61K9/16A61K9/20A61K9/48A61P35/00
Inventor 徐无为陆正鑫
Owner QIDONG GAITIANLI MEDICINES
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