Vessel sealing device and methods

A vascular, central tube technique used in the field of closing the lumen of hollow anatomical structures such as blood vessels

Inactive Publication Date: 2009-07-29
BOSTON SCI LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As a result, many thermal ablation catheters have not been routinely use

Method used

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  • Vessel sealing device and methods
  • Vessel sealing device and methods
  • Vessel sealing device and methods

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0091] The device was connected to the generator via an adapter cable and used between 1-40W in watts, the minimum power wattage was determined by various applications of the catheter in bovine liver tissue. This can be determined as 5 watts.

[0092] The catheter was introduced into the liver tissue; the RF generator was set to 5 watts and power was applied. A timer was started to record the time it took for the impedance reading to increase by 10% above baseline, which was considered sufficient to coagulate tissue. When the impedance rating is reached, the RF generator is placed in standby mode. Coagulated tissue was excised and the area of ​​tissue coagulated was measured. The catheter was repositioned and the procedure was repeated ten times. The results showed a continuous heating zone around the electrodes with no blind spots.

[0093] The results are described in the table below:

[0094] Table 1

[0095] experiment

[0096] 4

example 2

[0098] Variation of distance between electrodes: Figure 20 (a) shows the pattern of tissue coagulation obtained with two variants of the bipolar configuration of the catheter tip in bovine liver tissue. It can be seen that at 5 watts of RF energy, with a distance of 10 mm between the proximal and distal electrodes, separation and distinct ablation points are obtained. At a distance of 7 mm between the electrodes (again 5 watts), the ablation points converge to give a single elongated ablation zone. Figure 20 (b) in (b) shows the result of a monopolar configuration where the conduit in which the electrodes are mounted is supplemented by a remote grounding pad. The extended ablation zone is shown by arrow G.

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Abstract

A device is provided that is suitable for percutaneous insertion into a hollow vessel, such as a blood vessel, within the body of a patient for purpose of causing endoluminal closure of the vessel at a specified therapeutic site in the body of a patient. The device suitably is in the form of a catheter that is slidably mounted on a guidewire. The catheter may comprise one or more heating modules, as well as one or more extendable structures located on the device and optionally on the associated guidewire, that lead thermal ablation of the vessel walls and subsequent collapse of the vessel. The catheter can function alone or in cooperation with an associated guidewire to induce sealing of the vessel. Methods of using the catheter to treat lesions such as tumours or haemorrhages are also described.

Description

technical field [0001] The present invention relates to devices and methods for performing percutaneous catheter-based interventional surgery. In particular, the present invention relates to methods and apparatus for closing the lumen of hollow anatomical structures, such as blood vessels. Background technique [0002] Blocking blood vessels is beneficial in many medical conditions such as arteriovenous malformations and varicose veins. In the treatment of liver disease, liver regeneration can be promoted by directing the blood supply from one area to another, for example by blocking portal vein blood from reaching the right liver to induce hypertrophy of the left liver. Blocking blood flow can be used in the field of oncology, especially in the field of treating tumors. One way to treat tumors is to interrupt the blood supply to the tumor. In many tumors there are a small number of scattered vessels that supply blood to the tumor. Blocking these vessels stops the supply...

Claims

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Application Information

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IPC IPC(8): A61B17/08A61B18/18
Inventor 纳吉·哈比卜
Owner BOSTON SCI LTD
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