Traditional Chinese medicine combination capable of preventing and treating seborrheic dermatitis and preparation and preparation method thereof

Abstract

The invention relates to a Chinese medicinal composition for preventing and treating seborrheic dermatitis, which comprises the following raw medicines in portion by weight: 20 to 50 weight portions of pseudolarix, 25 to 45 weight portions of kuh-seng, 10 to 20 weight portions of clove, 10 to 20 weight portions of cinnamon, and 30 to 60 weight portions of Cacumen Platycladi. According to clinical observation and experimental verification, the Chinese medicinal composition can effectively prevent and treat the seborrheic dermatitis. After two weeks treatment, symptoms such as erythema, pruritus and scale are improved markedly, and statistical analysis shows that the total effective rate of the tested medicament is 75.24 percent and the total effective rate of the contrasted medicament (Caile lotion, Xian Yangsen Pharmaceutical Ltd.) is 58.10 percent; and after four weeks treatment, the total effective rate of the tested medicament is 85.71 percent, and the total effective rate of the contrasted medicament is 65.71 percent, so that the treatment effect of the tested medicament is obviously higher than that of the contrasted medicament. The relapse rate of the seborrheic dermatitis is only 1.9 percent within one month after the medicament of the invention is stopped, and is low compared with 5.7 percent of the relapse rate of the contrasted medicament; and no allergic symptom occurs during the observation period, so that the medicament has high safety. The Chinese medicinal composition has good application prospect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition capable of effectively preventing and treating seborrheic dermatitis, an external preparation prepared from the composition and a preparation method thereof, belonging to the field of traditional Chinese medicine. Background technique [0002] 1. About seborrheic dermatitis and its harm [0003] Seborrheic dermatitis (SD) is a common chronic papular-squamous inflammatory skin disease that often involves skin areas rich in sebaceous glands such as the scalp, face, neck, and upper trunk. The incidence rate of this disease population is 1%~3%, young people is 3%~5%, and the male is more than the female. Among patients with AIDS-related diseases, the incidence rate of this disease is as high as 32% to 83%. In addition, this disease is more likely to occur in patients with neurological diseases, such as mental disorders, Parkins...

AI Technical Summary

Problems solved by technology

(4) Ciclopirox amine cream, 0.77% ciclopirox gel: when the ointment drug is applied to scalp seborrheic dermatitis, it is inconvenient to use

(5) 4% rasoxine shampoo, pyrithione zinc shampoo, selenium sulfide shampoo: the clinical efficacy is not very satisfactory, and the side effect of dry hair is prone to occur, and the recurrence rate is high

But there are also many deficiencies at the same time: there are certain limitations in the selection of drugs, that is, most of the selected drugs are heat-clearing, detoxifying and damp-drying; most of the traditional Chinese medicines used in research are water decoctions or crude extracts, from which effective The number of components is small; there are few large-scale, systematic, randomized, double-blind, and multi-center clinical trials, most of which are only for clinical efficacy observation; they do not start from basic experimental research, but directly rise to clinical research, lacking foundation Evidence support and corroboration of the microscopic aspects of the study

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