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Medical moisturized eye paste and method for preparing same

An eye patch, hydrophilic polymer technology, applied in medical science, ophthalmic treatment, absorbent pads, etc., can solve the problems of cumbersome eye care methods, waste of medical staff's time, side effects, etc., to prevent exposure keratitis , No toxic side effects, good biocompatibility

Active Publication Date: 2009-09-02
都本立
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The invention mainly solves the problems of cumbersome eye care methods for patients with non-ocular surgery, pain for patients, waste of time for medical staff, high cost and side effects, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Example 1. Mix 8g PVA and 92g purified water, heat in a water bath at 90°C to prepare an 8wt% aqueous solution, pour the aqueous solution into a mold, cure at -6°C for 24h, place at 20°C for 72h, use γ-ray or electron beam Irradiation 15kGy sterilization package sealed.

[0034] The water content of the medical moisturizing eye protection patch of Example 1 is 83%; the thickness of the prepared moisturizing eye protection patch is 2.9mm; at 37°C and a relative humidity of 55%, the water vapor transmission rate is 1500g / m 2 .24h; the tensile strength is 220g / cm 2 .

Embodiment 2

[0035] Example 2: Mix 10g PVA and 90g purified water, heat in a water bath at 90°C to prepare a 10wt% aqueous solution, pour the aqueous solution into a mold, cure at -4°C for 24h, place at 25°C for 48h, use γ-ray or electron beam The package is sealed and sterilized after irradiation with 25kGy.

[0036] The water content of the medical moisturizing eye care patch of Example 2 is 80%; the thickness of the prepared moisturizing eye care patch is 4.1mm; at 37°C and a relative humidity of 55%, the water vapor transmission rate is 1750g / m 2 .24h; tensile strength is 280g / cm 2 .

Embodiment 3

[0037] In Example 3, 12g PVA and 88g purified water were mixed, heated in a water bath at 90°C to prepare a 12wt% aqueous solution, poured into a mold, cured at 0°C for 24h, placed at 30°C for 48h, and irradiated with γ-ray or electron beam According to 35kGy sterilization packaging and sealing.

[0038] The water content of the medical moisturizing eye care patch of Example 3 is 79%; the thickness of the prepared moisturizing eye care patch is 4.5mm; at 37°C and a relative humidity of 55%, the water vapor transmission rate is 1230g / m 2 .24h; Tensile strength is 310g / cm 2 .

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Abstract

The invention discloses a medical moisturized eye paste and a method for preparing the same. The medical moisturized eye paste is characterized in that according to weight percentage, 8 to 25 percent of hydrophilic macromolecular material and 75 to 92 percent of water are mixed, placed for 10 to 24 hours at a temperature of between 6 below zero and 10 DEG C, placed for 48 to 72 hours at a temperature of between 10 and 60 DEG C, cured and radiated by gamma-rays or electron beams with radiation dosage of between 15 and 120 kGy to prepare the medical moisturized eye paste; and the prepared medical moisturized eye paste has a thickness of between 2.5 and 6.0 millimeters, meets the shape of the structure in the periphery of human eyes, can be operated disposably, has long using time, can provide relatively closed humid environment, has good biocompatibility, innocuity, no sensitization, no toxicity and no side effect, has no residue after being used, does not need to clean skin and hair of patients and has simple operation.

Description

Technical field: [0001] The invention relates to the technical field of medical auxiliary materials, in particular to a medical moisturizing eye-protecting patch and a preparation method thereof. It is suitable for general anesthesia patients and deep coma patients who do not undergo eye surgery, and can prevent exposure keratitis caused by muscle relaxation. . Background technique: [0002] At present, for non-eye surgery patients under general anesthesia and deep coma, the ways to prevent exposure keratitis caused by muscle relaxation can be divided into three categories: 1. Intraoperative wet saline coverage, this method cannot block bacteria , It is not waterproof, and the effect is not obvious enough. More importantly, it is necessary to have someone responsible for long-term replacement of the dried saline gauze, and the saline is also easy to enter the eyes, causing great pain to the patient; 2. Apply syrup and ointment, such as tetracycline eye Ointment, this method needs...

Claims

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Application Information

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IPC IPC(8): A61F9/00A61F13/02A61L15/32A61L15/30A61L15/28A61L15/26A61L15/24A61L15/20
Inventor 都本立宋玉叶杨毅姜红朱锐纪学英许文明李颖
Owner 都本立
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