Ziziphora clinopodioides Lam. total flavonoid extract and production method thereof and application thereof in cardiovascular drug

A production method and technology of new tower flowers are applied in the field of medicine to achieve the effects of reducing costs, saving resources and improving curative effect

Inactive Publication Date: 2010-01-13
XINJIANG INST OF MATERIA MEDICA
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  • Abstract
  • Description
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  • Application Information

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Problems solved by technology

[0007] The present invention provides an extract of total flavonoids of aromatic xinta flower and its production method and the application of cardiovascular drugs, which overcomes the above-mentioned deficiencies in the prior art, solves the prob

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  • Ziziphora clinopodioides Lam. total flavonoid extract and production method thereof and application thereof in cardiovascular drug
  • Ziziphora clinopodioides Lam. total flavonoid extract and production method thereof and application thereof in cardiovascular drug
  • Ziziphora clinopodioides Lam. total flavonoid extract and production method thereof and application thereof in cardiovascular drug

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Embodiment Construction

[0020] The present invention is not limited by the following examples, and the specific implementation manner can be determined according to the above-mentioned technical solutions and actual conditions of the present invention.

[0021] 1. Extraction of total flavonoids extract of aromatic Xinta flower

[0022] 1.1 Extraction

[0023] Grind and sieve the fragrant Xintahua dried medicinal material through a 10-mesh sieve to a 50-mesh sieve, add 6 to 12 times by weight of water or 30% to 90% ethanol aqueous solution, soak until the heart is clear, and heat to a slight boil to reflux Extract 1 to 4 times, 0.5 hours to 2.5 hours each time, combine the extracts, place them at room temperature, filter, concentrate the filtrate under reduced pressure to 1 to 3 times the weight of the dry medicinal material, and pass the concentrated solution through a macroporous adsorption resin column , subsequently, at room temperature, with 6 times to 12 times by weight of water, 6 to 12 times ...

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Abstract

The invention provides a ziziphora clinopodioides Lam. total flavonoid extract and a production method thereof and the application thereof in cardiovascular drug. The ziziphora clinopodioides Lam. total flavonoid extract is obtained by the following method: extracting ziziphora clinopodioides Lam. dried crude drugs by using water or ethanol, absorbing by a macroporous resin column, decompressing, condensing and drying to obtain powdery dried aromatic ziziphora clinopodioides Lam. flavonoid extract with the color from yellow to claybank. The obtained extracts of ziziphora clinopodioides Lam. extract can be applied to the preparation of cardiovascular drugs, and can lower the yield (the taking dosage is reduced, the used crude drugs for reaching the same drug effect is reduced), thereby greatly saving ziziphora clinopodioides Lam. resources and reducing the cost while improving the healing effect.

Description

1. Technical field [0001] The invention relates to the technical field of medicine, and relates to an extract of total flavonoids of aromatic xinta flower, a production method thereof and the application of cardiovascular drugs. 2. Background technology [0002] Ziziphora clinopodioides Lam., also known as lip vanilla and mint, is a plant of the genus Ziziphora clinopodioides Lam. Growing on gravel slopes and semi-desert grasslands. It is distributed in Xinjiang in my country, and also in the former Soviet Union and Mongolia abroad. According to historical records, the whole herb of fragrant Xintahua is used as medicine. It is pungent in taste and cold in nature. We have systematically studied the chemical components of the aromatic xinta flower in the early stage, showing that the aromatic xinta flower contains a large amount of flavonoids, and the flavonoids have a wide range of pharmacological activities. At present, the role of flavonoids in cardiovascular diseases has...

Claims

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Application Information

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IPC IPC(8): A61K36/53A61P9/00
Inventor 杨伟俊满尔哈巴石峰何江阿不都沙拉木
Owner XINJIANG INST OF MATERIA MEDICA
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