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A system, computer-readable medium, method, and use for combined epithelial early cancer diagnosis and staging

一种上皮、癌症的技术，应用在医疗诊断领域，能够解决适用性有缺陷等问题

Inactive Publication Date: 2010-02-03
KONINK PHILIPS ELECTRONICS NV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0014]Therefore, both DPS morphology and LSS morphology are flawed in their suitability for detecting early stages of cancer development

Method used

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  • A system, computer-readable medium, method, and use for combined epithelial early cancer diagnosis and staging
  • A system, computer-readable medium, method, and use for combined epithelial early cancer diagnosis and staging
  • A system, computer-readable medium, method, and use for combined epithelial early cancer diagnosis and staging

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Embodiment Construction

[0032] Several embodiments of the present invention will be described in more detail below with reference to the accompanying drawings in order to enable those skilled in the art to practice the present invention. However, this invention may be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art. These embodiments do not limit the invention, but the invention is only defined by the appended patent claims. Furthermore, the terminology used in the detailed description of the particular embodiments shown in the drawings is not intended to limit the invention. figure 1The principles for known diffusion path length spectroscopy configurations are shown. The DPS mod can take two modes, single scatter case or multiple scatter case. The photon path length l ...

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Abstract

A system (40) for diagnosis and staging of early stages of cancer in the tissue of a patient is provided. The system- is configured to combine information from a Polarized Light Scattering Spectroscopy measurement (70) having a first probe depth, and a Differential Path Length Spectroscopy measurement (60) having a second probe depth, wherein the second probe depth is set larger than' the first probe depth. By comparing the results of the Polarized Light Scattering Spectroscopy and Differential Path Length Spectroscopymeasurements early stages of cancer, such as dysplasia may be detected. Alsohyperplasia, carcinoma in situ, and carcinoma may be detected. A computer-readable medium, method and use are also provided.

Description

technical field [0001] The present invention relates generally to the field of medical diagnostics. More specifically, the present invention relates to a system, computer readable medium and method for detection and staging of early stage cancer by combined differential path length spectroscopy and polarized light scattering spectroscopy. Background technique [0002] Cancer is one of the top three causes of death in the world. More than 85% of all cancers have epithelial origin, meaning they are closely associated with surfaces. An example is skin. The skin is composed of three primary layers: the epidermis, which provides waterproofing and serves as a barrier against infection; the dermis, which serves as the site of the skin's attachments; and the hypodermis, the subcutaneous fat layer, also known as the basement membrane. [0003] The epidermis is the outermost layer of the skin. It forms a waterproof, protective covering on the surface of the body and is composed of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B1/273A61B5/00G01N21/25
CPCA61B5/0075G01N2021/4792G01N21/4795A61B5/0084
Inventor A·T·M·范戈夫B·H·W·亨德里克斯H·周M·M·J·W·范赫彭
Owner KONINK PHILIPS ELECTRONICS NV
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