Composition for tooth-surface anticaries repair and preparation method thereof

Abstract

The invention provides a composition for tooth-surface anticaries repair and a preparation method thereof, and relates to a composition. The invention provides the composition taking tetracalciumphosphate and dicalcium phosphate as main raw materials for tooth-surface anticaries repair, and the preparation method thereof. The composition comprises calcification agent powder and solidification liquid, wherein the mass ratio of the calcification agent powder to the solidification liquid is 0.1 to 10; the calcification agent powder comprises tetracalciumphosphate powder and dicalcium phosphate powder; the particle size of the calcification agent powder can be less than or equal to 50 mu m; the dicalcium phosphate can be dicalcium phosphate dihydrate or anhydrous dicalcium phosphate and the like; the solidification liquid may be at least one of water-soluble phosphate solution, citric acid solution, sodium alginate solution and the like; and the pH of the composition for tooth-surface anticaries repair can be 5 to 9. During preparation, the tetracalciumphosphate powder and the dicalcium phosphate powder are mixed and ground to obtain the calcification agent powder; the solidification liquid is prepared; and the calcification agent powder is mixed with the solidification liquid to obtain the composition for tooth-surface anticaries repair.

Description

Composition for tooth surface caries prevention and restoration and preparation method thereof technical field The invention relates to a composition, in particular to a composition which can be used for tooth surface caries prevention and restoration and a preparation method thereof. Background technique Dental caries is a common name for dental caries. It is a progressive lesion of tooth hard tissue caused by the compound action of various factors in the oral cavity. It is manifested as demineralization of inorganic matter and decomposition of organic matter. There are many theories for the understanding of dental caries, including chemical bacteria theory, proteolysis theory, proteolysis-chelation theory, glycogen theory, and quadruple factor theory. At present, the quadruple factor theory is recognized, which points out that the pathogenesis of dental caries is related to four factors: host, bacteria, food and time, that is, the occurrence of dental caries requires sen...

AI Technical Summary

Problems solved by technology

Its operation is simple and easy, but the disadvantage is to remove the excess healthy teeth

The disadvantage of this method is that the paste is too acidic, which may damage the oral mucosa

S.Busch et al. (US Patent US20050220724A1; S.Busch, Angew.Chem.Int.Ed, 2004, 43(11): 1428-1431) started from the idea of ​​biomimetic mineralization, in the gelatin system, by regulating calcium, phosphorus In the diffusion process of fluoride ions, a 5 μm thick fluorine-based apatite coating is obtained on the enamel surface after 10 days. The disadvantage of this method is that the reaction cycle is too long and the operation is inconvenient.

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