Microemulsion composition and preparation method thereof
A technology of composition and microemulsion, which is applied in the direction of pharmaceutical formulations, cosmetic preparations, dressing preparations, etc., can solve the problems of micro-toxicity, and achieve the effects of small impact, transdermal penetration, and uniform dispersion
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Publication Date
- 2011-09-28
- Estimated Expiration
- Not applicable · inactive patent
Smart Images
Figure 1 Figure 2 Figure 3
Abstract
Description
technical field
[0001] The invention relates to a microemulsion composition and a preparation method thereof, and the microemulsion composition is suitable for the cosmetic industry. Background technique
[0002] The active ingredients of cosmetics determine its efficacy, but any cosmetic must be carried through a suitable carrier to exert its due effect. That is to say, the composition and properties of the cosmetic matrix directly affect the release, penetration and absorption of its active ingredients. Therefore, even with the same formula, the effects produced by different solvents are quite different.
[0003] Human skin mainly absorbs external substances through three ways: 1. Enter through hair follicles, sebaceous gland pores and sweat pores; 2. Enter directly through the keratinocyte membrane; 3. Enter through the gap between keratinocytes. Generally, the droplet of cosmetic emulsion is between 1-10 microns, and the active ingredients of the product cannot penetra...
Examples
Embodiment 1
[0040] Weigh raw materials according to the table:
[0041]
[0042] Step 1, heat component A to 75°C and stir evenly; at the same time, heat component B to 75°C;
[0043] Step 2, under stirring, slowly drop component B into component A, and stop heating when obvious blue light is observed;
[0044] Step 3, cooling the solution in step 2 until the temperature drops to 35° C., adding component C and stirring evenly to obtain a microemulsion composition.
Embodiment 2
[0046] Weigh raw materials according to the table:
[0047]
[0048] Step 1, heat component A to 85°C and stir evenly; at the same time, heat component B to 85°C;
[0049] Step 2, under stirring, slowly drop component B into component A, and stop heating when obvious blue light is observed;
[0050] Step 3, cooling the solution in step 2 until the temperature drops to 40°C, adding component C, stirring evenly to obtain a microemulsion composition;
[0051] Step 4, further cooling the solution in step 3 to room temperature, adding component D, and stirring evenly to obtain a microemulsion composition.
Embodiment 3
[0053] Weigh raw materials according to the table:
[0054]
[0055] Step 1, heat component A to 80°C and stir evenly; at the same time, heat component B to 80°C;
[0056] Step 2, under stirring, slowly drop component B into component A, and stop heating when obvious blue light is observed;
[0057] Step 3, cooling the solution in step 2 until the temperature drops to 45°C, adding component C, stirring evenly to obtain a microemulsion composition;
[0058] Step 4, further cooling the solution in step 3 to room temperature, adding component D, and stirring evenly to obtain a microemulsion composition.
[0059]The present invention adopts nonionic emulsifier, selects suitable grease, and the microemulsion composition droplet that forms is far smaller than emulsion droplet, and disperses more evenly, and the impact on external environment is little, more stable, therefore, can be used as solvent, has It is conducive to transdermal penetration and promotes the exertion of fun...