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Jinji blood stasis eliminating pills and preparation method thereof

A technology of honeysuckle and chronic pelvic inflammatory disease, which is applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of inconvenient taking, large dosage, easy deliquescence, etc.

Active Publication Date: 2012-05-23
HARBIN PHARMA GROUP SANJING QIANHE WANGKUI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Jinji Huayu Granules are used for the treatment of chronic pelvic inflammatory disease in women with symptoms of damp-heat accumulation and qi stagnation and blood stasis. The active ingredients of the drug are extracted by ordinary water extraction and alcohol precipitation, and then processed with pharmaceutically acceptable excipients and auxiliary materials. However, there are deficiencies such as incomplete extraction of active ingredients, large doses, inconvenient taking, and deliquescence.

Method used

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  • Jinji blood stasis eliminating pills and preparation method thereof
  • Jinji blood stasis eliminating pills and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Take 200g of honeysuckle, 200g of baicalin, 150g of dandelion, 100g of Viola chinensis, 150g of saponins, 150g of red peony, 200g of Caulis Spatholobus, 100g of Sanleng, 100g of Chuanxiong, cyperus (vinegar) 100g, Corydalis (vinegar) 100g, Wang No retention (stir-fried) 100g, add 8 times the amount of water of the original medicinal material, ultrasonically extract at 40°C for 1 hour, filter, filter the residue with 70% ethanol at 40°C for 1 hour, filter, combine the two filtrates, and concentrate at 70°C to obtain Extract, dry and pulverize, pass through a 100-mesh sieve, mix the drug and polyethylene glycol 4000 1:3, control the temperature of the material at 70°C, the condensation temperature at 2°C, the drop distance of 2.0cm, and the drop rate of 30 drops / minute, drop into In liquid paraffin, the drop pills are taken out after forming, the surface cooling liquid is absorbed, and dried to obtain 200 grams of drop pills.

specific Embodiment 2

[0024] Take 200g of honeysuckle, 200g of baicalin, 150g of dandelion, 100g of Viola chinensis, 150g of saponins, 150g of red peony, 200g of Caulis Spatholobus, 100g of Sanleng, 100g of Chuanxiong, cyperus (vinegar) 100g, Corydalis (vinegar) 100g, Wang No retention (fried) 100g, add 10 times the amount of water of the original medicinal material, ultrasonically extract at 60°C for 1 hour, filter, filter the residue with 80% ethanol at 60°C for 1 hour, filter, combine the two filtrates, and concentrate at 80°C to obtain Extract, dried and crushed, passed through a 100-mesh sieve, mixed according to the ratio of drug and polyethylene glycol 4000 1:3, controlled material temperature 90°C, condensation temperature 20°C, drop distance 4.0cm, drop speed 100 drops / min, drop into In liquid paraffin, the drop pills are taken out after forming, the surface cooling liquid is absorbed, and dried to obtain 200 grams of drop pills.

Embodiment 3

[0026] Take 200g of honeysuckle, 200g of baicalin, 150g of dandelion, 100g of Viola chinensis, 150g of saponins, 150g of red peony, 200g of Caulis Spatholobus, 100g of Sanleng, 100g of Chuanxiong, cyperus (vinegar) 100g, Corydalis (vinegar) 100g, Wang No retention (stir-fried) 100g, add 10 times the amount of water of the original medicinal material, ultrasonically extract at 50°C for 1 hour, filter, filter the residue with 80% ethanol at 50°C for 1 hour, filter, combine the two filtrates, and concentrate at 80°C to obtain Extract, dried and crushed, passed through 100 mesh sieve, mixed according to 1:3 of drug and polyethylene glycol 4000, controlled material temperature 80°C, condensation temperature 10°C, drop distance 3.0cm, drop speed 30 drops / min, drop into In liquid paraffin, the drop pills are taken out after forming, the surface cooling liquid is absorbed, and dried to obtain 200 grams of drop pills.

[0027] 1. The test method of the embodiment of Jinji Huayu Droppin...

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Abstract

The invention discloses traditional Chinese medicine Jinji blood stasis eliminating pills for treating a chronic pelvic inflammatory disease and a preparation method thereof. The Jinji blood stasis eliminating pill has effectively improved active components of medicaments and the advantages of less taking dosage, convenient taking and obvious curative effect. The preparation method is characterized by comprising the following steps of: with honeysuckle, baical skullcap root, dandelion, Chinese violet, Chinese honeylocust spine, common peony root, suberect spatholobus stem, common burreed rhizome, szechuan lovage rhizome, nutgrass galingale rhizome (vinegar), corydalis tuber (vinegar) and cowherb seed (frying) as raw materials, processing the raw materials by methods of ultrasonic extraction, concentration, drying, pulverization, and the like; and with polyethylene glycol-4,000 as an aqueous solution solid substrate and liquid paraffin as cooling liquid, uniformly mixing according to the ratio of the medicaments to the substrate of 1:3 to obtain the pills.

Description

(1) Technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to Jinji Huayu dripping pills for treating chronic pelvic inflammatory disease and a preparation method thereof. (2) Background technology [0002] Jinji Huayu Granules are used for the treatment of chronic pelvic inflammatory disease in women with symptoms of damp-heat accumulation and qi stagnation and blood stasis. The active ingredients of the drug are extracted by ordinary water extraction and alcohol precipitation, and then processed with pharmaceutically acceptable excipients and auxiliary materials. However, there are incomplete extraction of active ingredients, large doses, inconvenient taking, and deliquescence. (3) Contents of the invention [0003] In order to overcome the disadvantages of Jinji Huayu Granules, the present invention provides Jinji Huayu Dropping Pills with complete extraction of active ingredients, small dosage, convenient administratio...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/902A61K9/20A61P15/00
Inventor 王建军张爱民郑玉梅刘广和武凤梅费建军朱文军温立群李尚晏
Owner HARBIN PHARMA GROUP SANJING QIANHE WANGKUI PHARMA