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Multilayer composite artificial vascular membrane with shape memory function and preparation method thereof

An artificial blood vessel, multi-layer composite technology, which is applied in the fields of blood vessels, human tubular structure devices, medical science, etc., to achieve the effects of simplifying the surgical treatment process, low cost, and simple preparation method

Inactive Publication Date: 2011-01-26
DONGHUA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, aortic dissection and aneurysms occurring in the aortic arch face great challenges in surgical treatment due to the involvement of important branch vessels and other high-risk factors, so further improvement is needed. Simple branch grafts are the ultimate direction of development

Method used

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  • Multilayer composite artificial vascular membrane with shape memory function and preparation method thereof
  • Multilayer composite artificial vascular membrane with shape memory function and preparation method thereof
  • Multilayer composite artificial vascular membrane with shape memory function and preparation method thereof

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Experimental program
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Effect test

Embodiment 1

[0023] Such as figure 1 , figure 2 As shown, a new type of multi-layer composite artificial vascular membrane with shape memory function. The artificial vascular membrane is composed of three layers of PTT mesh fabric material with different density gradients as the core layer and polytetrafluoroethylene membrane as the inner and outer layers. The artificial vascular membrane formed by the core layer has a rapid shape recovery ability during the release process due to the gradient of the mesh modulus, so that the branch artificial vascular membrane has a shape memory function, which can be implanted in the body in conjunction with the aortic stent. After the artery is blocked, there is a significant blood pressure difference between it and the aorta, and its shape memory function is automatically released and breaks into the branch artery, reducing the difficulty of surgery.

[0024] A method for preparing a multilayer composite artificial vascular membrane, comprising:

...

Embodiment 2

[0030] Such as figure 1 , figure 2 As shown, a new multi-layer composite artificial vascular membrane with shape memory function, the artificial vascular membrane is made of PTT / PET twisted yarn mesh fabric material with different density gradients as the core layer and polytetrafluoroethylene membrane as the inner and outer layers The three-layer composite artificial vascular membrane, the core layer has a rapid shape recovery ability during the release process due to the gradient of the grid modulus, so that the branch artificial vascular membrane has a shape memory function, and it can cooperate with the aortic stent implantation. Into the body, there is an obvious blood pressure difference between the branch artery and the aorta after the branch artery is blocked, and its shape memory function is automatically released and breaks into the branch artery, reducing the difficulty of surgery.

[0031] A method for preparing a multilayer composite artificial vascular membran...

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Abstract

The invention relates to a multilayer composite artificial vascular membrane with a shape memory function and a preparation method thereof. The vascular membrane comprises a core layer, an inner layer and an outer layer, wherein the core layer is made of a material with a shape memory function; and the inner layer and the outer layer are polyfluortetraethylene membranes. The preparation method comprises the following steps of: using elastic fiber with the shape memory function as a base material of a textile; preparing a textile base covering membrane as the core layer of the artificial vascular membrane through a textile forming technology; carrying out mould pressing on the core layer, the inner layer and the outer layer by a mould; and preparing the integrative artificial vascular membrane. The invention has simple method and low cost and is suitable for industrialized production. The obtained vascular membrane is embedded into a body to cooperate an aorta stent, automatically releases and bursts into a branch artery by using the obvious blood pressure difference between the branch artery and a main artery after the branch artery is blocked, simplifies the whole operating process and reduces the surgery difficulty.

Description

technical field [0001] The invention belongs to the field of artificial vascular membrane and its preparation, in particular to a multi-layer composite artificial vascular membrane with shape memory function and its preparation method. Background technique [0002] At present, the methods commonly used to deal with branch artificial blood vessels in surgical operations include pre-fenestration technology, graft in situ puncture fenestration technology, hybrid surgery, etc., each of which has its own characteristics, and its purpose is to reduce surgical trauma and time. However, aortic dissection and aneurysms occurring in the aortic arch face great challenges in surgical treatment due to the involvement of important branch vessels and other high-risk factors, so further improvement is needed. Simple branch grafts are the ultimate direction of development. Contents of the invention [0003] The technical problem to be solved by the present invention is to provide a multi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/06A61L27/40A61L27/16A61L27/18A61L27/50
Inventor 王富军张雷王璐李毓陵黎聪李斌赵存屹罗汉峰曹正霞
Owner DONGHUA UNIV
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