Bioartificial liver support system and combined type liquid storage tank thereof

A liver support system, bioartificial technology, applied in the field of device and its combined liquid storage tank, and medical equipment, can solve the problem of affecting the material exchange efficiency between hepatic failure plasma and bioreactor, the interference of one-way flow of plasma in double chambers, and the extraction of Speed ​​limit and other issues, to achieve the effect of improving material exchange efficiency, avoiding invalid circulation, and stable operation
CN101966352AActive Publication Date: 2011-02-09ZHEJIANG UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
ZHEJIANG UNIV
Publication Date
2011-02-09

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Abstract

The invention discloses a bioartificial liver support system and a combined type liquid storage tank thereof, wherein the combined type liquid storage tank comprises a closed liquid inlet tank and a closed liquid return tank; the top of the liquid inlet tank is provided with a first liquid inlet and a first air pressure balancing hole; the bottom of the liquid inlet tank is provided with a first liquid outlet and a second liquid inlet; the top of the liquid return tank is provided with a third liquid inlet and a second air pressure balancing hole; the bottom of the liquid return tank is provided with a second liquid outlet and a third liquid outlet; and the second liquid outlet is communicated with the second liquid inlet by a first communicating pipe which is provided with a direction and flow control device. The invention can improve material interchange efficiency between hepatic failure blood plasma and a bioreactor, avoids futile cycle, does not need to depend on the chimney effect of pumps, has simple structure and stable operation and has improvement of the bioartificial liver support system. In the invention, volume of the liquid inlet tank and the liquid return tank can be adjusted according to specific requirements to suit clinical application.
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Description

technical field

[0001] The invention relates to a medical device for treating a bioartificial liver, in particular to a device capable of effectively improving the treatment effect of a bioartificial liver and a combined liquid storage tank thereof, belonging to the technical field of biomedicine. Background technique

[0002] The bioartificial liver support system is a device that provides extracorporeal liver function support for patients with liver failure. The emergence of this technology has opened up a new way for the treatment of liver failure. The basic principle is to place primary hepatocytes isolated in vitro (pig hepatocytes, human hepatocytes, etc.) or hepatocyte lines cultured in vitro (immortalized hepatocyte lines, etc.) Through material exchange between the semipermeable membrane with a certain molecular cutoff and liver cells, the therapeutic purpose of correcting metabolic disorders can be achieved. In this field, research on cell sources and bioreactors ...

Claims

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