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Compound combination medicament for treating cerebral metastatic tumor and preparation method and application thereof

A technology for brain metastases and drugs, which can be used in drug combinations, anti-tumor drugs, and medical preparations containing active ingredients, etc., can solve the problem of less anti-cancer effect, and achieve good clinical efficacy.

Inactive Publication Date: 2011-02-23
JIANGSU PROVINCIAL HOSPITAL OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In my country, traditional Chinese medicine preparations are very common in the treatment of malignant tumors, but there are not many drugs that have been confirmed by modern medicine to have positive anti-cancer effects, and even fewer of them have anti-cancer effects comparable to chemotherapy drugs

Method used

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  • Compound combination medicament for treating cerebral metastatic tumor and preparation method and application thereof
  • Compound combination medicament for treating cerebral metastatic tumor and preparation method and application thereof
  • Compound combination medicament for treating cerebral metastatic tumor and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A compound combination medicine for treating brain metastases, comprising the following components in parts by weight: 10 parts of Zhinanxing, 10 parts of Gecko, 15 parts of Pinellia, 15 parts of Shichangpu, 20 parts of Curcuma, 10 parts of Scorpion, pig Ling 30 parts, cyclodextrin 5 parts.

[0029] Weigh each flavor medicine of above-mentioned weight fraction, prepare as follows

[0030] (1) Boil Polyporus and Gecko with 6 times the weight of water, decoct twice for 1.5 hours each time, filter, and combine the filtrates;

[0031] (2) Put Acorus calamus and Zezhu into a decompression concentration tank, add 10 times the weight of water, soak for 30 minutes, distill and extract the volatile oil, the extraction time is 4 hours, store the volatile oil in a separate device for standby, filter the extract, and filter the residue for standby;

[0032] (3) Add the medicinal dregs obtained in step (2) into Pinellia and Southern Star, add water, decoct 2 times, the weight of ea...

Embodiment 2

[0040] A compound combination medicine for treating brain metastases, comprising the following components in parts by weight: 20 parts of Zhinanxing, 15 parts of Gecko, 30 parts of Pinellia, 30 parts of Shichangpu, 15 parts of Curcuma, 15 parts of Scorpion, pig Ling 20 parts, cyclodextrin 10 parts.

[0041] Weigh each flavor medicine of above-mentioned weight fraction, prepare as follows

[0042](1) Boil Polyporus and Gecko with 10 times the weight of water, decoct twice for 2 hours each time, filter, and combine the filtrate;

[0043] (2) Put Acorus calamus and Zezhu into a decompression concentration tank, add 14 times the weight of water, soak for 40 minutes, distill and extract the volatile oil, the extraction time is 6 hours, store the volatile oil in a separate device for standby, filter the extract, and filter the residue for standby;

[0044] (3) Add the medicinal dregs obtained in step (2) into Pinellia and Southern Star, add water, decoct 2 times, the weight of each...

Embodiment 3

[0052] A compound combination medicine for treating brain metastases, comprising the following components in parts by weight: 30 parts of Zhinanxing, 15 parts of Gecko, 30 parts of Pinellia, 30 parts of Shichangpu, 45 parts of Curcuma, 9 parts of Scorpion, pig Ling 45 parts, cyclodextrin 15 parts.

[0053] Weigh each flavor medicine of above-mentioned weight fraction, prepare as follows

[0054] (1) Boil Polyporus and Gecko with 8 times the weight of water, decoct twice for 1 hour each time, filter, and combine the filtrate;

[0055] (2) Put Acorus calamus and Zezhu in a decompression concentration tank, add 9 times the weight of water, soak for 30 minutes, distill and extract the volatile oil, the extraction time is 5 hours, store the volatile oil in another device, and set aside, filter the extract, and filter the residue for standby;

[0056] (3) Add the medicinal dregs obtained in step (2) into Pinellia and Southern Star, add water, decoct 2 times, the weight of each addi...

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Abstract

The invention discloses a compound combination medicament for treating cerebral metastatic tumor. The medicament comprises the following components in part by weight: 20 to 50 parts of processed arisaema root, 10 to 30 parts of gecko, 20 to 40 parts of processed pinellia tuber, 20 to 40 parts of grass-leaf sweelflag rhizome, 30 to 50 parts of zedoary, 5 to 15 parts of scorpion, 40 to 60 parts of agaric and 5 to 15 parts of cyclodextrin. The invention also discloses a preparation method for the compound combination medicament for treating the cerebral metastatic tumor and application thereof to preparation of the medicament for treating the cerebral metastatic tumor. The compound combination medicament for treating the cerebral metastatic tumor has good clinical curative effect and has no obvious adverse response.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound and its preparation method and application, in particular to a compound medicine for treating brain metastases and its preparation method and application. Background technique [0002] Brain metastases refer to the metastases of primary malignant tumors in other extracranial tissues and organs. According to statistics, the incidence of brain metastasis of malignant tumors is 25% to 35%. Among organ metastasis of tumors, the incidence of brain metastasis ranks third after lung and liver. Brain metastases account for about 10% of all brain tumors. The incidence of tumor brain metastasis is different in different medical institutions, according to clinical autopsy reports, it is 30%-60%. The most common primary tumor is lung cancer, accounting for about 50% of brain metastases, followed by breast cancer, accounting for about 15%. [0003] Currently, the treatment of brain metastases incl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K35/64A61P35/04A61K35/646
Inventor 王瑞平邹玺刘志辉朱超林胡玥
Owner JIANGSU PROVINCIAL HOSPITAL OF TCM
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