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Traditional Chinese medicine compound preparation for treating early hypertension kidney damage

A compound preparation and a kidney damage technology, which are applied in the field of traditional Chinese medicine compound preparations for treating early hypertensive kidney damage and their preparation, to achieve the effects of reducing aggregation, regulating vascular endothelial function, and improving clinical symptoms

Inactive Publication Date: 2011-03-23
SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE PUTUO DISTRICT CENT HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the current clinical treatment, there is no ideal drug that can effectively control blood pressure and protect target organ damage. Research and screening of the above ideal drugs has very important clinical significance and is attracting increasing attention

Method used

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  • Traditional Chinese medicine compound preparation for treating early hypertension kidney damage
  • Traditional Chinese medicine compound preparation for treating early hypertension kidney damage
  • Traditional Chinese medicine compound preparation for treating early hypertension kidney damage

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Weigh 20g of Rehmannia glutinosa, 10g of Eucommia ulmoides, 20g of Sangjisheng, 15g of Achyranthes bidentata, 20g of apocynum, 12g of kudzu root, and 10g of Uncaria according to the formula ratio. Soak until it is an inch above the level of the medicine, soak for 30 minutes, use strong fire (quick fire) before the medicine is boiled, and change to slow fire (slow fire) after boiling, the first decoction starts from boiling for 30 minutes, the second decoction for 20 minutes, and then filter out twice Mix the medicinal solution, about 400ml, and take it twice in the morning and evening.

Embodiment 2

[0024] Weigh 30g of Rehmannia glutinosa, 20g of Eucommia ulmoides, 30g of Sangjisheng, 20g of Achyranthes bidentata, 30g of apocynum, 20g of kudzu root, and 20g of Uncaria according to the formula ratio. Soak until it is an inch above the level of the medicine, soak for 30 minutes, use strong fire (quick fire) before the medicine is boiled, and change to slow fire (slow fire) after boiling, the first decoction starts from boiling for 30 minutes, the second decoction for 20 minutes, and then filter out twice Mix the medicinal solution, about 400ml, and take it twice in the morning and evening.

Embodiment 3

[0025] Embodiment 3 clinical experiment

[0026] 1 research object

[0027] All the cases were 90 patients who were treated in the outpatient clinic and ward of the Department of Internal Medicine of Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine from January 2007 to February 2008. They were divided into three groups according to the openness of the random number table. Combination of western medicine group (Yishen Pinggan Formula + Luotingxin) and Western medicine control group (Luodingxin), of which 30 cases were in the Chinese medicine treatment group, 19 males and 11 females; average age (51.32±5.73) years old; hypertension The course of disease ranged from 4 to 28 years, with an average of (16.3±1.75) years. 30 cases in the Chinese and Western medicine control group, 21 males and 9 females; the average age was (53.21±5.43) years; the course of hypertension was 5 to 30 years, with an average of (15.6±1.36) years; 10 females; average age ...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine compound preparation for treating early hypertension kidney damage and a preparation method thereof, belonging to the field of traditional Chinese medicine pharmacy. A mixed medicinal liquid is prepared from traditional Chinese medicinal plants of rehmanniae vaporata, eucommia ulmoides, loranthus parasiticus, uncaria, apocynum venetum, kudzu vine roots and medicinal cyathula roots through soaking and water decoction according to the pathological nature that the symptoms of early hypertension kidney damage mainly comprise primary deficiency, secondary excess, upper excess and lower deficiency. Auxiliary materials can be furthered added to prepare granules, tablets or capsules. The test result of clinic treatment verifies that the compound preparation can obviously improve the clinical symptoms of hypertension kidney damage patients, alleviate the histomorphologic changes of the kidney and protect damaged kidney and has obvious curative effect of pressure reduction on early hypertension kidney damage.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine pharmacy, and relates to a compound traditional Chinese medicine preparation for treating early hypertensive kidney damage and a preparation method thereof. Background technique [0002] Hypertension is a common and frequently-occurring disease in clinical practice, and the resulting damage to target organs such as the heart, brain, and kidneys is the main cause of disability and death. The kidney is one of the target organs of high blood pressure. Generally speaking, most patients with high blood pressure lasting for more than 5 years have different degrees of kidney damage. With the further development of the disease, renal insufficiency occurs, and eventually develops into uremia, which endangers the life of the patient. . A clinical survey conducted in the United States in 1998 showed that in the past 10 years, hypertensive renal damage has become one of the main reasons for the ra...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P9/12A61P13/12
Inventor 刘龙民朱喜英梁贤栋胡宗仁常晓铁刘淑清黄太权罗家祺刘薇薇徐开蕾袁易王为祥殷佩浩韩吉
Owner SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE PUTUO DISTRICT CENT HOSPITAL
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