Prescription of low-dose condensed type Mai jun an tablet or capsule and preparation thereof

Abstract

The invention provides maijun'an tablets or capsules for lowering blood pressure which have more significant effect, safety, and no toxicity or side effect, thus achieving the purpose of effectively lowering the blood pressure under the situation of taking smaller dose. The adopted method is to respectively carry out separation and purification of active ingredients for lowering the blood pressure in kudzuvine root and gambir plant, thus obtaining total flavonoids of the kudzuvine root with the purity of over 80 percent and total alkaloids of the gambir plant with the purity of over 50 percent. 8g / 500g of hydrochlorothiazide, 260g / 500g of the total flavonoids of the kudzuvine root, 120g / 50g of total alkaloids of the gambir plant and 112g / 500g of auxiliary agents are added for preparing tablets, pills or capsules. The concentrated maijun'an tablets or capsules of the invention do not only have small administration dose, but also have significant efficacy, controllable quality and easily quantified indicators, thus facilitating the standardized production of the pharmaceutical composition preparation for lowering the blood pressure.

Description

Concentrated Maijunan tablet or capsule formula with small dosage and preparation method thereof technical field The invention relates to a traditional Chinese medicine prescription for reducing blood pressure and a preparation method thereof, in particular to a concentrated Maijun'an tablet or capsule formula with a small dosage and a preparation method thereof. Background technique Hypertension is a common disease, frequently-occurring disease. With the improvement of living standards, changes in dietary structure, and accelerated pace of work, the incidence of hypertension has gradually increased. At present, most of the antihypertensive drugs commonly used by hypertensive patients are chemical drugs, which have many side effects and are prone to drug resistance after long-term use. The commonly used antihypertensive Chinese patent medicines have the disadvantages of taking large doses and slow onset of effect. The prescription of Maijunan preparation (tablets and caps...

AI Technical Summary

Problems solved by technology

However, the preparation method of the above-mentioned Maijunan preparation is relatively backward, and the two kinds of Chinese medicinal materials (Uncaria, Puerariae) are simply crushed, partially extracted, and then mixed with hydrochlorothiazide and supplementary materials according to the prescribed dosage.

Therefore, the Maijunan preparations currently produced and sold all have problems such as complex components, unstable preparation quality, and large dosages.